Fission yeast NDR/LATS kinase Orb6 regulates exocytosis via phosphorylation of the exocyst complex

Sawin lab paper featured in Cell Rep.

Image
Image from Sawin paper, Cell Rep 2019

Authors

Tay YD, Leda M, Spanos C, Rappsilber J, Goryachev AB, Sawin KE

Summary

NDR/LATS kinases are known primarily for their role in controlling cell and tissue proliferation and morphogenesis, e.g. via regulation of transcription in the Hippo pathway. Using fission yeast S. pombe as a model system, Tay et al. show that the NDR/LATS kinase Orb6 is a major regulator of exocytosis.

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