Centre research publications from 2010. Splicing-dependent RNA polymerase pausing in yeast Beggs lab paper featured in Molecular Cell. RiboSys, a high-resolution, quantitative approach to measure the in vivo kinetics of pre-mRNA splicing and 3'-end processing in Saccharomyces cerevisiae Beggs lab paper featured in RNA. Fission Yeast Mto1 Regulates Diversity of Cytoplasmic Microtubule Organizing Centers Sawin lab paper featured in Current Biology. A catalytic role for Mod5 in the formation of the Tea1 cell polarity landmark Sawin lab paper featured in Current Biology. Several novel nuclear envelope transmembrane proteins identified in skeletal muscle have cytoskeletal associations Schirmer lab paper featured in Molecular Cell Proteomics. Orphan CpG islands identify numerous conserved promoters in the mammalian genome Bird lab paper featured in PLoS Genetics. The leukocyte nuclear envelope proteome varies with cell activation and contains novel transmembrane proteins that affect genome architecture Schirmer lab paper featured in Molecular Cell Proteomics. The protein composition of mitotic chromosomes determined using multiclassifier combinatorial proteomics Rappsilber lab paper featured in Cell. Loss of Topoisomerase I leads to R-loop-mediated transcriptional blocks during ribosomal RNA synthesis Tollervey lab paper featured in Genes & Development. A Genetic Engineering Solution to the Arginine Conversion Problem in Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC) Sawin lab paper featured in Molecular & Cellular Proteomics. CpG islands influence chromatin structure via the CpG-binding protein Cfp1 Bird lab paper featured in Nature. A super-resolution map of the vertebrate kinetochore Earnshaw lab paper featured in Proceedings of the National Academy of Science USA. Cracking pre-40S ribosomal subunit structure by systematic analyses of RNA-protein cross-linking. Tollervey lab paper featured in EMBO Journal. Recruitment of MBD1 to target genes requires sequence-specific interaction of the MBD domain with methylated DNA Stancheva lab paper featured in Nucleic Acid Research. Yeast pre-rRNA processing and modification occur cotranscriptionally Tollervey lab paper featured in Molecular Cell. Stc1: a critical link between RNAi and chromatin modification required for heterochromatin integrity Allshire lab paper featured in Cell. Neuronal MeCP2 Is Expressed at Near Histone-Octamer Levels and Globally Alters the Chromatin State Bird lab paper featured in Molecular Cell. The Final Step in 5.8S rRNA Processing Is Cytoplasmic in Saccharomyces cerevisiae Tollervey lab paper featured in Molecular and Cellular Biology. Architecture of the RNA polymerase II-TFIIF complex revealed by cross-linking and mass spectrometry Rappsilber lab paper featured in EMBO Journal. Cell-specific and lamin-dependent targeting of novel transmembrane proteins in the nuclear envelope Schirmer lab paper featured in Cellular and Molecular Life Sciences. This article was published on 2024-06-17