Centre research publications from 2014. Long non-coding RNA-mediated transcriptional interference of a permease gene confers drug tolerance in fission yeast Allshire lab paper featured in Nature Communications. Trim25 Is an RNA-Specific Activator of Lin28a/TuT4-Mediated Uridylation Centre lab paper featured in Cell Reports. Genome-wide distribution of RNA-DNA hybrids identifies RNase H targets in tRNA genes, retrotransposons and mitochondria Tollervey lab paper featured in PLoS Genetics. A cell suicide module: Auxin-induced rapid degradation of Inhibitor of Caspase Activated DNase (ICAD) induces apoptotic DNA fragmentation, caspase activation and cell death Earnshaw lab paper featured in Jornal of Biological Chemistry. Sister kinetochores are mechanically fused during meiosis I Marston lab paper featured in Science. Activation of the g-Tubulin Complex by the Mto1/2 Sawin lab paper featured in Current Biology. Tension-dependent removal of pericentromeric shugoshin is an indicator of sister chromosome biorientation Marston lab paper featured in Genes & Development. Lin28a regulates neuronal differentiation and controls miR-9 production Rappsilber lab paper featured in Nature Communications. A splicing-dependent transcriptional checkpoint associated with pre-spliceosome formation Beggs lab paper featured in Molecular Cell. Shugoshin biases chromosomes for biorientation through condensin recruitment to the pericentromere Marston lab paper featured in eLife. This article was published on 2024-06-17
