Tollervey lab paper featured in PLoS Genetics. Image Authors Holmes, R.K., Tuck, A.C., Zhu, C., Dunn-Davies, H.R., Kudla, G., Clauder-Munster, S., Granneman, S., Steinmetz, L.M., Guthrie, C. and Tollervey, D. Summary This paper reports that loss of the of major pre-mRNA binding protein Npl3 resulted in transcriptional termination defects at diverse RNAs in yeast , with readthrough observed on large subsets of both mRNAs and ncRNAs. These termination cause widespread changes in gene expression, both through inappropriate termination and through transcriptional interference at neighbouring genes. Related links DOI Journal Link This article was published on 2024-06-17
