A novel microtubule nucleation pathway for meiotic spindle assembly in oocytes

Ohkura paper featured in Journal of Cell Biology.

Image
Image from Ohkura paper, Journal of Cell Biology 2018

Authors

Romé, P., Ohkura, H.

Summary

The paper reports discovery of a novel microtubule nucleation pathway for meiotic spindle assembly in oocytes.  It is active specifically in oocytes but not in mitotic cells, and acts complementarily to the Augmin pathway.  Spatial regulation of this pathway is critical to restrict the spindle assembly to the vicinity of chromosomes in oocytes.

Related links

Journal Link

Ohkura Lab Website

DOI