Brr2p-mediated conformational rearrangements in the spliceosome during activation and substrate repositioning

Beggs lab paper featured in Genes & Development.

Image
Image from Beggs paper, Genes & Development 2012

Authors

Daniela Hahn, Grzegorz Kudla, David Tollervey and Jean D. Beggs

Figure: An analysis of Brr2 helicase interactions and functions by UV-crosslinking and sequencing (CRAC) and RNA-seq with wild-type and mutant Brr2

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