Schirmer lab paper featured in Molecular Cell. Image Authors Robson, M.I., de Las Heras, J.I., Czapiewski, R., Le Thanh, P., Booth, D.G., Kelly, D.A., Webb, S., Kerr, A.R., and Schirmer, E.C. Summary Muscle-specific nuclear envelope transmembrane proteins (NETs) were shown to specifically direct the repositioning of genes to the nuclear periphery during myogenesis where the peripheral positioning roughly doubles the amount of gene repression. Genes so regulated require tight temporal regulation during differentiation and accordingly combined knockdown of these NETs blocks muscle differentiation. Related links Journal Link This article was published on 2024-06-17
