Structural evidence for Scc4-dependent localization of cohesin loading

Marston lab paper featured in eLife.

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Image from Marston paper elife 2015

Authors

Hinshaw, S.M,, Makrantoni, V,, Kerr, A,, Marston, A.L,, Harrison, S.C.

Summary

This paper describes structural analysis of the Scc2/Scc4 cohesin loader. A conserved patch on Scc4 is found to be important for targeting cohesin loading to centromeres.

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