Molecular architecture of the Dam1 complex–microtubule interaction

Welburn lab paper featured in Open Biology.

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Image from Welburn paper Open Biology 2016

Authors

Thibault Legal, Juan Zou, Alicja Sochaj, Juri Rappsilber, Julie P. I. Welburn

Summary

In this paper Legal, et al. reveal the architecture of the yeast kinetochore 10-protein Dam1 complex. They show that the C termini of Dam1 and Duo1 are necessary and sufficient for binding of the Dam1 complex to microtubules, revealing the minimal requirements for a robust microtubule-kinetochore interface.

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