Global analysis of transcriptionally engaged yeast RNA polymerase III reveals extended tRNA transcripts

Tollervey lab paper featured in Genome Research.

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Image from Tollervey paper, Genome Research 2016

Authors

Turowski, T.W., Leśniewska, E., Delan-Forino, C., Sayou, C., Boguta, M., Tollervey, D.

Summary

We report the mapping of the location of RNAPIII along all nascent transcripts. This revealed strikingly uneven polymerase distributions across transcription units and a substantial level of long, 3´-extended forms due to read-through of the canonical poly(U) terminators.

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