Ohkura lab paper featured in Development. Image Metaphase I spindles in wild type (right) and incenp mutant (left) oocytes, B. Blue, DNA; Green, tubulin; Red, pole protein D-TACC Authors Colombié N, Cullen CF, Brittle AL, Jang JK, Earnshaw WC, Carmena M, McKim K, Ohkura H Development 135, 3239-3246 Summary In many animals including humans during female meiosis spindle formation takes place independently of centrosomes. Chromosomes play a central role in spindle assembly. In this article the Ohkura lab uses live imaging to demonstrate that the chromosomal passenger protein Incenp has a role in acentrosomal spindle formation. Related links Journal link This article was published on 2024-06-17