Innovative tools and technologies available for commercial development. Image The quality of our research is reflected in the technologies and other intellectual property currently available for licensing or collaborative research and development.Search current opportunitiesReagents and antibodiesImproved 'humanised' mouse modelsA genetic engineering strategy in mouse embryonic stem cells to replace large regions of mouse chromosomal sequences (>100kb) with the corresponding human syntenic region.Monoclonal antibody to streptavidin-binding proteinA monoclonal antibody to the streptavidin-binding epitope tag widely used in affinity purification of proteins.Analysing the methylation status of human genesNovel CGI-enrichment technology using two protein domains that isolate methylated and non-methylated CpG islands (CGIs).Live attenuated Salmonella for vaccine developmentOur method of producing safer, more effective, live attenuated Salmonella bacterial vaccines could be applied to the development of better vaccines for this and other infectious diseases.Stem cellsDefined media for culturing regionalised anterior endoderm cellsOur defined media and serum-free process for isolating anterior definitive endoderm cells from mouse embryonic stem cells could improve the derivation of key gut-associated organ cells and provide a new set of gene profiling markers for directed differentiation.Haematopoietic stem cell expansionA method for producing large quantities of haematopoietic stem cells from tissues in the laboratory that could potentially be used to treat a wide variety of blood disorders and cancers.Non-viral method for creating induced pluripotent stem cellsOur safer, non-viral plasmid vector for generating induced pluripotent stem cells by introducing the four genes required for reprogramming of somatic cells in a single fragment; the genes can be removed following reprogramming.MBD3-deficient embryonic stem cell lineA pluripotent (murine) embryonic stem cell line, which can be maintained in the absence of any exogenous factors and stimulated to differentiate into identifiable bone, muscle, skin, fat and neuronal tissue.Contact UsThe School's Business Development Team, based within Edinburgh Innovations, are the first point of contact for any questions related to industry interactions and collaborations. Business Development Team - School of Biological Sciences Edinburgh Innovations Contact details Email: SBS-BD@ei.ed.ac.uk Web: Edinburgh Innovations This article was published on 2024-06-17