Information on application and requirements for Electron Microscopy and Cryo-EM. The electron microscopy facilities of the core allow researchers to image biological assemblies from atomic to cellular scale. Our core activities are built around cryogenic single-particle imaging to determine macromolecular structures. Traditionally, this has been carried out using purified preparations of the protein of interest, but techniques such as cryo-electron tomography allow direct imaging of suitable targets in their cellular environment. We also provide support for preparation and imaging of ultra-thin sections from conventionally embedded and stained specimens, as well as more general room temperature imaging of both biological and non-biological materials. Cryo-Electron Microscopy Room-temperature Microscopy Electron Diffraction This article was published on 2025-09-23
