EastBio Student Cohort 2024

Find out more about our 2024 student intake.

image of 2024 eastbio cohort at induction event

Find information about the EastBio 2024 student cohort and their PhD projects, organised by Thematic Area.

Clean Growth

University of Edinburgh, Centre for Regenerative Medicine

Project Title

Reconditioning discarded human donor livers using machine perfusion: novel technologies to increase the pool of donor organs

Primary Supervisor

Prof. Stuart Forbes and Dr Sofia Ferreira-Gonzalez

Project Summary

Liver transplantation is often the only curative treatment for patients with end-stage liver disease, but donor shortage remains a challenge.

This project aims to expand the pool of transplantable livers by reconditioning those deemed unfit for transplantation. We will employ a novel cell therapy to resolve tissue damage, using alternatively activated macrophages to repair necrosis and senolytics to eliminate senescent cells. These therapies will be applied during normothermic machine perfusion to restore and improve organ viability.

Personal Note

I’m from Germany but have spent the last few years in Austria, where I studied medicine and later trained as a transplant surgeon. Now, I’m diving into my next big adventure with this PhD! The project excites me for its potential to directly impact patient care, and its innovative approach to cell therapy aligns perfectly with my passion for research in regenerative medicine and transplantation.

Outside of work, I have a strong passion for outdoor sports—from skiing to hiking and diving, also I love spending time with my friends. Above all, I’m always seeking new perspectives, whether through travel experiences, or great conversations.

Image of Madita outside with a snowy background

University of Edinburgh

Project Title

Building Baselines for Terrestrial Biodiversity: calibration and testing of eDNA for the biodiversity of temperate rainforest

Primary Supervisor

Dr Catherine Kidner

Personal Note

I'm from Hertfordshire near London, and I did my undergraduate/masters degree in Biology at the University of St Andrews. In general I'm interested in projects involving functional traits, evolution, and conservation. Outside of work I enjoy dancing and painting my nails :)

University of St Andrews

Project Title

Interfacing Biocompatible Photochemistry with Microbial Metabolism

Primary Supervisor

Dr Craig Johnston

Project Summary

This EASTBIO project is co-supervised by Dr. Craig Johnston at the University of St Andrews and Dr. Stephen Wallace at the University of Edinburgh. We are currently working at the interface between organic chemistry and synthetic biology, combining microbial production of metabolites that can be used as starting materials in photochemical reactions.

Personal Note

Hi, I'm Yating from China:) I graduated from University College London with a first-class MSci in Medicinal Chemistry in 2023, after completing my dissertation on the development of macrocycle-based HIV-1 inhibitors supervised by Prof. David Selwood. I then worked as a research assistant in Prof. Billy Ng's lab at the Chinese University of Hong Kong, focusing on developing bifunctional molecules for endogenous O-GlcNAcylation. Outside the lab, I enjoy cooking, spending time with friends, watching TV dramas, and playing table tennis.

University of Edinburgh

Project Title

A physics-based and data-driven approach to the rational design of molecular glues

Primary Supervisor

Prof. Julien Michel

Project Summary

Molecular glues are drugs designed to break down troublesome oncoproteins via the ubiquitin-proteasome degradation mechanism. The aim of this project is to develop free-energy and docking which may aid in rational strategies for screening for molecular glues.

Personal Note

Benedict grew up in Edinburgh, and enjoys playing badminton in his free time.

Crops and Soil

University of Edinburgh

Project Title

Assessing and explaining plant invasion distribution across French Polynesian islands

Primary Supervisor

Dr Guillaume Latombe

Project Summary

My PhD project concerns plant invasion in the French Polynesian islands, where invasive alien species are a major threat to biodiversity. I will implement species distribution models, factoring in environmental variables such as climate and topography, and compare model predictions to actual invasion levels to determine which islands are more or less invaded than predicted. Furthermore, I will investigate whether different invasive species underperform or overperform relative to expected performance given their environmental preferences. Analysis of these discrepancies will incorporate socioeconomic factors, such as trade, population density, and agricultural practices, to investigate which factors are the key drivers of plant invasion in the French Polynesian islands.

Personal Note

Hello, my name is Eve! I first developed an interest in how maths can be used to understand patterns and processes in biology during my undergraduate degree in maths and statistics at the University of Glasgow. I had the opportunity to explore this in greater depth during my Master’s degree at Heriot-Watt university where I studied several courses in mathematical ecology and completed my dissertation on mathematical modelling of ecological regime shifts. I then worked at Forest Research, where I used statistical modelling to better understand the influence of genotype and environment on selected traits of silver birch trees. In my free time I enjoy reading, walking, and playing piano.

University of Dundee

Project Title

Opening the door to disease: how plant pathogen virulence proteins enter host cells

Primary Supervisor

Prof. Paul Birch

Project Summary

My project involves defining the mechanism by which plant pathogen proteins, effectors, enter the cell. Previous work has demonstrated that this is done via clathrin-mediated endocytosis. My job now for the next four years to get into the specifics of how this takes place. I hope to do this through a mixture of proteomics and imaging techniques, and also have fun along the way!

Personal Note

I'm from North Yorkshire originally but then moved onto Edinburgh to study Plant Science. After graduating, I moved onto the John Innes Centre to undertake a predoctoral internship over six months and then to a Masters in Research still in Norwich. I like to boulder and run - I am currently aiming to complete all 70 Scottish park runs over my four years in Dundee!

University of Edinburgh, School of Chemistry

Project Title

Understanding the Source of Flavour in Peated Scotch Whisky

Primary Supervisor

Dr Nicholle Bell

Project Summary

Compounds derived from the burning of peat form a core part of the flavour profile of Scotch Whisky, an industry estimated to contribute more than £7bn to the UK economy annually. As concerns around the sustainability of the industry have grown, however, the extraction and burning of peat has garnered close attention due to the ecological and carbon-storing importance of peatlands. It is therefore important to gain a clear understanding of how the distinctive flavours of ‘peated’ whisky arise in order to improve the efficiency of peat use and identify potentially viable alternatives. This project seeks to apply recently developed methodologies for the analysis of complex mixtures at the University of Edinburgh, Heriot-Watt, and Scotch Whisky Research Institute, using high-resolution spectroscopic techniques such as NMR and FT-ICP-MS to characterise ‘peated’ whisky flavours and understand they arise and evolve across the various stages of whisky production, from peat bog to bottle.

Personal Note

Growing up in New Zealand with Glaswegian parents means I was never far from the influence of Scottish culture from TV, to music, and (eventually) Whisky. Once I made the call to return to Scotland for university, I inevitably fell deep into the rabbit hole of whisky geek-ery. During my chemistry studies, I began to develop a keen interest into sustainability and analytical chemistry, while simultaneously delving deeper into the whisky industry, working in whisky shops, bars, and eventually at a distillery. However, once I saw an opportunity to combine my passions in an EASTBIO PhD project, I jumped at the chance, and look forward to the next four years of delving into the complex chemistry of Scotland’s national drink.

I look forward to fuelling my studies with specialty coffee, regular highland whisky adventures, and allowing plenty of downtime to indulge in my love of sci-fi films and retro games.

University of Aberdeen

Project Title

Biofortified Rice: Exploring genetic variation within aus rice to increase grain micronutrient density

Primary Supervisor

Dr Gareth Norton

Project Summary

The project focuses on enhancing the micronutrient density of rice, a vital global food crop. Rice lacks essential micronutrients like vitamin A, zinc, and iron, which are crucial for human health. By examining genetic variation in aus rice, the research aims to identify genes governing these nutrients and explore methods to boost their levels. Genome-wide association studies on rice populations will pinpoint genes related to grain zinc content through quantitative trait loci analysis. Bioinformatic tools will aid in gene selection. Pot experiments will be carried out to test growth conditions and soil amendments that enhance these vital nutrients. This study addresses the nutritional deficiencies in rice, aiming to fortify it with essential micronutrients crucial for combating malnutrition worldwide.

Personal Note

I am a Zimbabwean agronomist with a BSc in Agronomy and a Master's in Crop Science (Plant Breeding), dedicated to advancing agricultural practices. Combining my academic expertise with practical fieldwork, and having gained experience as an agronomist and research assistant, I have honed crop management and breeding skills. From optimizing crop yields to exploring innovative cultivation techniques, I am committed to enhancing agricultural productivity. Beyond professional pursuits, I find joy in the intricacies of farming and seek to contribute meaningfully to the agricultural landscape, ensuring food security and fostering agricultural growth in Zimbabwe and beyond.

SRUC

Project Title

Unravelling the mechanisms of plant-driven degradation of crop protection compounds

Primary Supervisor

Dr Luis Novo

Project Summary

My PhD Project:- ""Unravelling the mechanisms of plant-driven degradation of crop protection compounds."" aims to explore the interactions between soil chemistry, microbial populations, and plant physiology to develop sustainable strategies for enhancing phytoremediation in agriculture.

Personal Note

I’m from London and driven by a passion for knowledge and personal growth. I’m inspired by the innovative strategies being implemented in the developing agricultural world and would be honoured to contribute to modern breakthroughs in this field. Outside of academia, I enjoy reading and writing, which I’ve channelled into founding my own literary company. This blend of motivation and ambition drives both my academic and personal pursuits.

University of Aberdeen

Project Title

Easy peasy? Regenerating soil carbon with peas in the crop rotation

Primary Supervisor

Dr Sylvia Vetter

Project Summary

My project will work in collaboration with my CASE partner Birdseye to assess the impact of peas on soil health. The project will focus more specifically on the impact that adding peas to the crop rotation can have on nitrogen and carbon uptake in soils and how this can benefit future crop growth and mitigate greenhouse gas emissions.

Personal Note

Before moving to Aberdeen for my PhD I was living in Durham and I graduated from Durham University with a BSc in Biosciences in 2024. During this degree I undertook a years placement at ADAS where I worked as a Field Research Scientist and developed my interest in the area of crop research and soil science, and this led me to apply to this project. Outside of my PhD I enjoy rowing which I do as part of Aberdeen's student rowing club.

Health

University of Edinburgh, IQB3

Project Title

Establishing a Synthetic Receptor-Based Detection Platform for Bacterial Pathogens in Mammalian Cells: A Novel Approach Towards Antibacterial Cell Therapy

Primary Supervisor

Dr Elise Cachat

Project Summary

My research is a proof of concept focused on developing a mammalian cell line equipped with a synthetic receptor detection platform. I will focus on engineering the platform to detect and respond to pathogenic bacterial surface antigens, with the long-term goal of applying it as an antibacterial cell therapy to combat the rise of antimicrobial resistance (AMR).

Personal Note

Hi, I’m Zuniara. With a background in biomedical sciences, I’ve always been drawn to exploring innovative approaches to tackling major health challenges, particularly antimicrobial resistance (AMR). During my internships, I worked with novel approaches such as phage therapy to address AMR. My interest in further exploring this, along with an appreciation for Scotland’s natural beauty, brought me to Edinburgh, where I joined Dr. Elise Cachat’s lab during my master’s. I worked on synthetic biology applications to develop a platform for detecting bacterial antigens. The lab’s supportive and collaborative atmosphere made my experience both rewarding and inspiring, motivating me to continue for my PhD. Now, I’m excited to dive deeper into my research, explore more of Scotland’s hidden gems, and enjoy its vibrant café culture, all while sharing experiences with the wonderful people I’ve met here.

University of Aberdeen

Project Title

Does the time of day that exercise is performed influence glycaemic outcomes across different phases of the menstrual cycle?

Primary Supervisor

Dr Brendan Gabriel

Project Summary

My PhD project explores the relationship between glycaemic control and exercise chronobiology across different phases of the menstrual cycle. We aim to understand the physiological interactivity between these simultaneously occurring biological rhythms and the subsequent effects on exercise. This project holds significance in maximising the exercise potential of healthy females, as well as in the case of disease management whereby exercise is often used as a therapeutic tool. Cutting-edge wearable technology will be utilised in the project to obtain data parameters such as physical activity, sleep, glucose levels and heart rate variability. This project has been developed in collaboration with industry partner Aparito, a data science company who have developed a novel App to record and analyse participant data from clinical/study trials. During my placement we aim to address real-world concerns regarding menstruation research and using PPI we aim to develop an efficient approach to recording menstrual cycle data.

Personal Note

I’m Lara and I’m originally from the Scottish Highlands but have lived in Aberdeen since I started my academic journey in 2017. I have strong ties to The University of Aberdeen having initially graduated with MA English, before completing my MSc in Human Nutrition. Subsequently, I embarked on a 1-year Teaching Assistant role within the School of Medicine, Medical Sciences and Nutrition which has ultimately led to this PhD. My journey leading up to this point has been unconventional but pursuing my varied interests has allowed me to develop a diverse skillset which has found its home in cross-disciplinary research, allowing me to pursue a field that I am extremely passionate about. Outside of academia, I like to keep active with bodybuilding, pole dancing and swing dancing. I also enjoy reading and spending time with my friends.

University of Edinburgh

Project Title

Investigating Sex Difference in Nuclear Lamin Levels and Their Impact on Macrophage-Regulated Inflammation and Severity of Lamin-Linked Disease

Primary Supervisor

Dr Steve Jenkins

Project Summary

My PhD project is investigating sexual dimorphisms in nuclear lamin protein abundances, and how these affect macrophage function and severity of lamin-linked diseases. Lamin proteins are key components of the nuclear envelope, known to play roles in cell motility, mechanical sensing, chromatin organisation and regulation of gene expression. Lamin gene mutations are responsible for more disease phenotypes than any other gene.My project firstly aims to characterise sex differences in nuclear lamin levels, then investigate how these differences contribute to dimorphisms in immune cell function and outcome of infection/inflammation.

Personal Note

I am from Scotland, and studied my BSc and MScR degrees here in Edinburgh. In my spare time I enjoy long distance running and work part time in community pharmacy.

University of Aberdeen

Project Title

The many actions of RAR ligands to protect against neurodegeneration - control of neuroinflammation, the blood brain barrier, and the potential connection with gut microbiota

Primary Supervisor

Prof. Peter McCaffery

Project Summary

My project will explore the importance of neuroinflammation, the blood brain barrier, and the possible influence of the gut microbiome on the action of retinoic acid receptor ligands as treatments for neurodegenerative disorders, with a particular focus on motor neuron disease. This research is highly interdisciplinary, within both academia and industry. I will be spending a duration of my third or fourth year in industry with Nevrargenics at the University of Durham, where I will explore the pharmacology of newly designed retinoic acid receptor ligands using novel mathematical modelling techniques.

Personal Note

I have recently graduated from the University of Aberdeen with an MSci in Pharmacology, with my industrial placement year being undertaken at the Industrial Biotechnology Innovation Centre's (IBioIC) scale up facility in Edinburgh. Originally from Aberdeen, I am excited to continue my studies at the UoA's Institute of Medical Sciences. Outside of academia and in my free time, I can be found mountain biking down my local trails, or rock climbing and bouldering.

University of Dundee

Project Title

The nose knows: Understanding coupling of olfactory receptors with G alpha proteins using a combination of AlphaFold and genetics

Primary Supervisor

Dr Varsha Singh

Project Summary

Hyposmia, reduction in the sense of smell, affects individuals with neurodegenerative disorders like Alzheimer's and Parkinson's Disease as well individual with common cold and COVID-19 infection. In humans, olfaction is mediated by the G-protein coupled receptors (GPCRs), although the function of many GPCRs remains unknown. Two unanswered questions in the field of olfaction are: (i) identity of odour ligands for orphan GPCRs (ii) uncovering the molecular details of GPCR-ligand interactions. My doctoral research focuses on understanding the molecular mechanisms of olfaction, leveraging both In silico and In vivo studies. In my project, I aim to elucidate how odorants bind to olfactory GPCRs, alter their conformation, and trigger downstream signalling. To bypass ethical issues and cost associated with research in humans, I aim to use a nematode, Caenorhabditis elegans, to study GPCR-odour interactions. Ease of genetic manipulation and functional assays in C. elegans, makes it an ideal organism for this study.

Personal Note

I am Shravan Rathod from India. I hold an honours degree in Chemistry and completed my master’s in Analytical Chemistry in 2013. After qualifying for national eligibility tests (CSIR NET/GSET) for lectureship, I was recruited as an Assistant Professor in the Department of Chemistry at Smt. S. M. Panchal Science College, Gujarat, where I taught undergraduate and postgraduate students for 7-8 years. During this time, I developed an interest in Structural Bioinformatics and collaborated on several projects. In 2022, I moved to London to pursue an MRes in Structural Biology at Birkbeck, University of London, where I gained wet lab experience and worked on COPII-mediated protein transport from the ER to the Golgi. In September 2024, I joined the University of Dundee as an EASTBIO PhD student. In my spare time, I enjoy reading about the history of fundamental research in STEM.

University of Aberdeen

Project Title

Molecular control underpinning arm and leg size, development and regeneration

Primary Supervisor

Prof Neil Vargesson

X - @sarah_nreh

University of St Andrews

Project Title

Uncovering the rules of dispersal and the consequences for the distribution, dynamics, and persistence of pathogens and their hosts.

Primary Supervisor

Dr Chris Sutherland

Project Summary

My research focuses on understanding the dynamics of pathogens and their hosts - vital for managing disease risk at a broad scale. I will investigate the interplay between host population dynamics and pathogen evolution, focusing on how spatial and demographic factors influence these interactions.

Using a long-term study of Bartonella infections in rodents (Assynt, Northwest Scotland), I will explore the spatial distribution of two hosts: the water vole, a habitat specialist, and the field vole, a more widespread species. This unique setting, characterized by distinct habitats for each host, allows us to examine how multi-host dynamics in a classic metacommunity impacts Bartonella persistence. Our 25-year dataset includes capture-recapture data for over 6,500 voles, host-specific infection information, and genetic analysis of Bartonella genotypes. With this wealth of data, I will integrate insights from genomics, epidemiology, and statistical ecology to enhance our understanding of vector-host-pathogen interactions and advance ecological and epidemiological theory.

Personal Note

I was born and raised in London, and earned both my Bachelors (Hons) in Zoology and MRes in Ecology at the University of Nottingham. Both of my research projects dove into the wonderful world of host-parasite interactions, finding my niche and what excites me early on.

I am passionate about making science accessible, so I jumped straight into a sci-comms role in regenerative medicine, followed by a year in open access publishing at Taylor & Francis. I am still the volunteer Communications Officer for the British Ecological Society's Climate Change Special Interest Group, but ultimately found that research has been calling for my return! I love my new lifestyle at St Andrews, and when I'm not at my desk thinking about parasites, you can find me running the coastal path, taking pictures of the sky, or painting whatever inspires me.

X - @ElsecallerMegan

University of Edinburgh, Roslin Institute

Project Title

Tracking the evolution, spread and key drivers of zoonotic diseases

Primary Supervisor

Dr Lu Lu

Project Summary

My PhD project is to integrate genetic and epidemiological data to quantify the evolution, transmission, and spread patters of H5 highly pathogenic avian influenza in cross-species transmission interfaces. This will primarily involve using and developing phylodynamic, statistical, and machine learning models to assess the impact of environmental factors, land use, human behaviour and other relevant factors on the emergence and spread of avian influenza.

Personal Note

Although a wet lab biologist in background, I transitioned to computational biology in 2021 when I immigrated to Scotland to attain my master's degree in bioinformatics at the University of Glasgow. After my degree, I was employed at the Center for Virus Research under Prof David Robertson where I was introduced to computational virology and became powerfully interested in the field. I'm excited to continue my academic journey in the subject at the Roslin Institute. When not doing virology, I enjoy the outdoors, horse-riding, and cuddling my two kitties.

University of Dundee

Project Title

Investigating Cryptosporidium oocyst suture formation and function in transmission

Primary Supervisor

Dr Mattie Christine Pawlowic

Project Summary

Cryptosporidium parvum is a zoonotic protozoan parasite that can infect both humans and cattle. It is a leading cause of morbidity and mortality for both groups, and additionally for agriculture it has a large economic impact. Cryptosporidium parasites are waterborne and transmitted inside microscopic eggshell-like structures called oocysts. The shell protects parasites against disinfectants and common water treatments, including chlorination. Once ingested by a host, four parasites emerge from a zipper-like opening in the oocyst wall called the suture. Parasites infect the intestine, causing diarrhoeal disease. There are no vaccines or effective treatment options available for both humans and cattle.

Little is understood about oocyst construction and composition. How Cryptosporidium parasites build their suture and then “unzip” is unknown. This project will focus on characterising the first identified markers of the oocyst suture using genetics and microscopy. We aim to understand how parasites form the suture and what its function is during infection versus transmission. This research has the potential to inform how we can interrupt infection and stop parasites spreading from one host to the next.

Personal Note

Sarah graduated with a MBiol in Biology from the University of York in 2023. During her degree she completed a Generation Research funded summer studentship in the Faria Lab at the York Biomedical Research Institute. During this time, she investigated the role of RNA in biomolecular condensate assemblies in African trypanosomes. This sparked a keen interest in parasitology research! After graduating, she worked for 12 months as a Research Technician at the University of Dundee in the Mattie Christine Pawlowic Lab studying a new parasite - Cryptosporidium. Thanks to UKRI BBSRC funding she’s now completing a PhD as an EastBio student and continues to research Cryptosporidium. Outside of the lab, her personal interests include reading, crafting and zumba.

University of Edinburgh, School of Chemistry

Project Title

Race Against Antimicrobial Resistance –Targeting the Gram-negative Outer Membrane with Peptides and Peptidomimetics

Primary Supervisor

Dr Annamaria Lilienkampf

Project Summary

Rising rates of antimicrobial resistance worldwide presents an urgent threat to public health. Novel treatment options are lacking and are urgently required, particularly against Gram-negative bacteria. My multidisciplinary PhD project involves chemistry and molecular microbiology, and is focused on finding targets in the outer membrane of Klebsiella pneumoniae, a pathogen of particular concern highlighted by the WHO. The aim of my project is to develop novel antimicrobial peptides to induce or regain antimicrobial susceptibility, ultimately to broaden future treatment options against antimicrobial resistant Gram-negative pathogens.

Personal Note

Hi, I'm Katrien – originally from Glasgow, I completed my Masters in Medical Microbiology at the University of Glasgow in 2018. Before moving to Edinburgh, I was a research assistant at the University of Cambridge, where I worked in collaboration with GSK to develop a small intestinal organoid model for studying enteric infections and disease. More recently, I was privileged to join the Tres Cantos Open Lab Foundation in Madrid, Spain, to investigate combination antimicrobial therapy in treating invasive non-typhoidal Salmonella. Thanks to the EASTBIO DTP funding, I am pursuing my PhD with the Lilienkampf and Schneiders groups, to continue my research in strategically tackling antimicrobial resistance. Outside of work, I enjoy cycling long and short distance trails, camping, bouldering, checking out local coffee shops and bakeries, as well as going to pub quizzes!

University of Aberdeen, Institute of Medical Sciences

Project Title

Investigating the effect of maternal inflammation on cortical inhibitory neuron development using 3D human brain cultures: Implications in Autism spectrum disorder

Primary Supervisor

Dr Daniel Berg

Project Summary

Maternal immune activation (MIA), triggered by infections or disease during pregnancy, can increase the risk of neurodevelopmental disorders such as autism spectrum disorder (ASD). Although the underlying mechanisms of ASD are poorly understood, one proposed cause is an imbalance in neuronal excitation and inhibition (E/I) in the brain. Animal studies have revealed that MIA disrupts the development of inhibitory cortical GABAergic interneurons, a cell type strongly associated with ASD. During fetal brain development, interneurons are generated from a population of neural stem cells located in the ganglionic eminences of the ventral subpallium from where they migrate to the cortex, navigating a complex environment along the way. I will apply 3D cell and tissue culture systems of the human brain, combined with omics approaches, to investigate the cellular and molecular mechanisms by which MIA influences various stages of inhibitory neuron development and subsequent E/I imbalance.

Personal Note

I come from a town in Southwest Finland, where I completed my education before moving to Scotland for my university studies. I earned my BSc (Honours) degree in Biomedical Sciences with Anatomy from the University of Aberdeen. I always thought I would pursue medicine, but the excitement of discovering new things and early opportunities to engage in research led me to decline my medical school offer and direct my focus on research. During my undergraduate studies, I joined the Kang and Berg group as a volunteer research assistant, taking my first steps into research. Another influential experience on my journey was participating in the 2023 Amgen Scholars Program at Ludwig Maximilian University of Munich where, I had the privilege of being a summer student in the Keays lab. Outside the lab I enjoy reading, studying languages, traveling to interesting places and hiking.

University of Edinburgh

Project Title

The role of the Ubiquitylation machinery in stress response in Candida albicans

Primary Supervisor

Dr Vasso Makrantoni

Project Summary

Candida albicans is the most common human fungal pathogen. It thrives within a complex and dynamic host environment through efficient metabolic control. Regulation of this during infection is poorly understood, particularly the assimilation of glucose and alternative carbon sources simultaneously. With only three classes of antifungal drugs available and increasing resistance, understanding the mechanisms of resistance is a priority. Candida utilizes the Ubiquitin-Proteasome System to eliminate superfluous or toxic proteins, using the GID E3 Ubiquitin Ligase complex upon changes in carbon sources. Evidence from the Makrantoni lab suggests that Candida employs this complex during host infection, rewiring metabolic pathways and enhancing virulence.My project investigates the regulation of metabolic flexibility by the GID complex by characterizing substrates through genetics, proteomics, and biochemistry/crystallography, and how these substrates regulate metabolite flux using microfluidics. I will also test how GID-mediated metabolic flexibility affects virulence and drug efficacy using in-vitro intestinal-organoid infection model systems.

Personal Note

I am originally from Essex, but have lived in various places, including the American Midwest and Nottingham, where I did an integrated master’s degree. My project focusing on cell division and replication in the malaria parasite. I particularly enjoyed doing research that had the potential to impact peoples lives, having also done an internship looking at the molecular genetics of myotonic dystrophy, so began looking for projects where I could continue this common thread. This project interested me the most and I was always hearing about how wonderful Edinburgh is, so I made the move back in August. Outside of the lab I enjoy running and hiking in Scotland’s many hills, wild camping, reading, and visiting cafes and Edinburgh’s many museums. I also play guitar occasionally and bake my own sourdough bread. I’m very excited to dive into postgrad research and meet my fellow students.

University of Edinburgh, Institute of Ecology and Evolution

Project Title

Immune regulation under pressure: Effects of diet on regulatory T cells in wild house mice

Primary Supervisor

Dr Iris Mair and Prof Amy Pedersen

Project Summary

My PhD project aims to investigate how nutrition influences immune regulation in wild house mice, particularly at barrier sites like the gastrointestinal tract and skin, which are constantly exposed to environmental stress. While the immune system is vital for fighting infections, excessive inflammation can lead to autoimmune diseases and allergies. Most immunological research relies on inbred lab mice, limiting our understanding of immune regulation in more complex, real-world environments. By studying wild mice through a dietary intervention in the field, this project will focus on how nutrition impacts immune regulation in a real-world environment, with an emphasis on the role of regulatory T cells, which are considered the master regulators of the immune system.

Personal Note

Hi, I’m Indra! I completed a BA in Biological Natural Sciences at the University of Cambridge and recently obtained an MSc by Research in Biomedical Sciences from the University of Edinburgh. While in Edinburgh, I developed a strong interest in Ecoimmunology research, a field that bridges ecology and immunology to understand better how the immune system interacts with the surrounding environment. I’m excited to continue exploring this interdisciplinary field in my PhD project. In my spare time, I enjoy hiking, reading, and experimenting in the kitchen with new recipes!

University of Edinburgh

Project Title

Investigating the physiological relevance of synaptic compensatory plasticity in freely behaving mice

Primary Supervisor

Dr Patricio Opazo

Project Summary

Alzheimer’s Disease (AD) is characterised by the loss of synapses in the brain, which strongly correlates with cognitive decline. My research surrounds the synaptic compensatory plasticity mechanisms that are implemented by the brain to counteract the loss of synapses in AD. In the lab, we have developed pathological and optogenetic tools to model this aspect of AD through the artificial elimination of synapses. This allows us to investigate synaptic loss and compensation over time using two-photon (2P) microscopy, both in-vitro and in-vivo. The focus of my research project is to determine the physiological relevance of synaptic compensation by combining in-vivo 2P imaging with highly advanced miniscope technology. These techniques will be used visualise and eliminate synapses in the brain in real time, during a freely moving behavioural task. This will allow us to investigate the effects of synaptic loss and compensation on neuronal cell function and ultimately behaviour in AD models.

Personal Note

I studied Pharmacology BSc at the University of Manchester, where I graduated during the pandemic. I spent the next year working in a Covid-19 sample testing lab, which was an eye opening experience. I moved to Edinburgh in 2021 to complete a Masters by Research in Neuroscience, where I fell in love with the City and the research! I have since been working as a Research Assistant for the last two years at the UK Dementia Research Institute, and will continue my work during my PhD in the same lab.

Livestock and Aquaculture

SRUC

Project Title

Nutritional sensitivity of intestinal antimicrobial peptide production for enhanced gut health in poultry

Primary Supervisor

Dr Farina Khattak

Project Summary

This project will involve investigating specific natural feed additives which have the ability to produce antimicrobial peptides in-situ and identify the mode of action which these antimicrobial peptides have in the gut. With the ever-growing global concern of antimicrobial resistance, this subject area is of importance as antimicrobial peptides could be used as a natural alternative to antibiotics.

Personal Note

I am from a family farm located in the Scottish borders. I have worked my way through SRUC initially gaining a HNC in animal care at Barony campus in Dumfries. I then carried out my undergraduate degree in animal science with SRUC based at kings buildings, Edinburgh, alongside this course I worked part time for SRUC veterinary services at St Boswells. On completion of my degree, I remained at kings buildings where I worked for a year as a trainee laboratory technician in biomarkers lab, this brings me to now where I begin my PhD journey. Out with studies and work, I enjoy spending time at home with family and the animals, and love being active and participating in sport.

University of Stirling, Institute of Aquaculture

Project Title

The Hidden Power of Mesenchymal Stromal Cells in Fish Skin

Primary Supervisor

Dr Rose Ruiz Daniels

Project Summary

Skin plays a crucial role in maintaining the overall health, welfare, and robustness of fish. Farmed fish face all manner of potential impacts on their skin integrity, including bacterial and parasitic infections, as well as physical injuries sustained during routine farming operations, treatments, and handling. New knowledge of the cellular composition and its genetic response to infection, wounding, and healing of fish skin is vital for devising strategies to improve healing outcomes in aquaculture settings. Due to the capability of mesenchymal stromal cells (MSCs) to differentiate into various cell types, as well as their roles in the inflammatory and remodelling phases of wound healing, they have become a promising candidate for regenerative therapies. This PhD aims to unravel the mystery of MSC differentiation as a pathway to advancement in novel therapies in farmed fish, focusing on salmonids.

University of Stirling

Project Title

Assessing the threat of antimicrobial resistance: A framework to support decision-making to ensure resilient aquaculture supplies

Primary Supervisor

Dr Andrew Desbois

Project Summary

Antimicrobial resistance (AMR) poses a significant threat to our ability to treat infections and is a pressing “One Health” issue affecting humans, animals, and the environment. This project aims to develop a tool to assess AMR risks in the aquaculture sector, the fastest-growing food production area globally. By investigating the UK seafood supply systems from “farm to fork,” I will identify where AMR threats arise and evaluate the actions taken by farmers, regulators, and processors. The focus will be on both locally produced commodities, such as Scottish salmon, and exotic products like shrimp. The goal is to work collaboratively with stakeholders to create an actionable tool that informs decision-making processes, helping to ensure the safety and resilience of food supplies against AMR threats.

Personal Note

I am from Essex, UK, and my academic journey began with a BSc in Zoology from the University of Exeter, where I focused my dissertation on CRISPR immunity and conjugative plasmids conferring resistance genes. I then pursued an MSc in One Health from the Royal Veterinary College (RVC) and the London School of Hygiene & Tropical Medicine (LSHTM), where my thesis examined the knowledge, awareness, and practices surrounding bovine tuberculosis in Nigerian pastoralists. My interests have increasingly centered on zoonosis, AMR, and developing resilient, sustainable food systems. I have also conducted fieldwork in Kenya, studying Tungiasis in marginalised communities. Outside academia, I enjoy keeping fit through running and horse riding—I have two horses! Additionally, I love reading and continuously learning new things, which keeps my curiosity alive.

University of Edinburgh

Project Title

Reducing the growing environmental impact of feeding dogs and cats

Primary Supervisor

Dr Peter Alexander

Project Summary

To meet climate change targets, food systems must radically change. It is suggested that over a quarter of the environmental damage from meat production relates to dog and cat food and that pet food production emits greenhouse gases equivalent to more than 6-17% of aviation worldwide. This is rising due to increased pet numbers and owners choosing foods with high meat contents, such as “grain-free” and “raw”. However, there has been very little research. There is no way to compare impacts of different pet foods to inform what are environmentally friendlier options. This study collects information on the ingredients of pet foods available within the UK, calculates the environmental impact of them in a way that can be repeated and used by others, and then looks at how owners might be supported to feed less environmentally damaging foods.

Personal Note

My background is as a practicing veterinary surgeon and working in the international development and animal welfare sectors. I have completed master’s degrees in international development and sustainability, and my research approach reflects this cross-disciplinary background.

Instagram

SRUC

Project Title

Behavioural and physiological impacts of harness design on dogs

Primary Supervisor

Dr Laura Dixon

Project Summary

The aim of the project is to quantify the impact of restrain and control devices on the behavioural and physiological indicators in dogs when pulling on the lead, greeting other dogs and people. The evaluation will utilise owned pet dogs recruited to the study to encompass ‘real world situations’.

Personal Note

I am a Clinical Animal Behaviourist specialising in dogs and hold a BSc in Zoology, an MSc in Applied Animal Behaviour and Welfare and a PG Cert in Animal Nutrition. I am director of Edinburgh Dog Behaviour Ltd, a company set up to consult on dog behaviour issues affecting pet owners and the wider community. Outside of work I love walking, travelling and yoga.

SRUC

Project Title

Genomic surveillance of antimicrobial resistance in UK cattle

Primary Supervisor

Dr Jack Hearn

Project Summary

My project explores the suitability of surveillance of antimicrobial resistance (AMR) from cattle across the United Kingdom as part of the Pathogen Surveillance in Agriculture, Food and the Environment (PATH-SAFE) program. I will analyse genomic data collected from recently sequenced isolates from predominant bacteria species to establish the prevalence and diversity of antimicrobial resistance genes (ARG) in cattle at slaughter. This will help establish risk to consumers of AMR pathogens acquired from cattle and guide foodborne pathogen monitoring policy once UK cattle are not routinely monitored for AMR and foodborne pathogens. Also, as CASE student, my project is in partnership with the UK Veterinary Medicine Directorate (VMD). I’m supervised by Dr Jack Hearn, Dr. Sue Tongue, both of SRUC and Dr. Deborah Hoyle of Roslin Institute.

Personal Note

Hello! I’m Larissa from Curitiba/ Brazil. After graduating in veterinary medicine from the Universidade Federal do Paraná, I participated in the residency program in infectious diseases in veterinary medicine at the Universidade Estadual de Londrina, which gave me the title of expert in this area. In the same university I did my master’s degree in Animal Sciences, with a focus on antimicrobial resistance (AMR), working to determine the presence of beta-lactam degrading enzymes in samples from animals of multiple species using phenotypic and genotypic tests. Now, I continue my studies in AMR with a focus on applied statistics and bioinformatics for genomic surveillance. In my free time I like to watch Flamengo football games, travel to different spots, go out with my friends and to church. I love well-prepared food, pets, beaches, chocolate and carnival.

ORCID

University of Stirling, Institute of Aquaculture

Project Title

Understanding loss of consciousness in decapod crustaceans for the optimisation of humane slaughter methods

Primary Supervisor

Dr Amaya Albalat

Project Summary

This project with the Institute of Aquaculture at the University of Stirling seeks to improve the welfare of decapod crustaceans by understanding unconsciousness and insensibility through the use of anaesthetic compounds and electrical stunning. Both methods have been gaining popularity in many crustacean species with the potential to improve their welfare, particularly in slaughter. This is of interest to the UK seafood sector; as of April 2022, the Animal Welfare (Sentience) Act came into force, recognising decapod crustaceans as sentient beings. As with vertebrates in the food industry, it is hoped that welfare measures will be legislated for decapod crustaceans in the UK both commercially and in science. This project aims to ensure ethical techniques have been thoroughly researched before the corresponding legislation catches up, benefitting the animals themselves and an economically important industry through suitable, humane methods that can be easily adopted.

Personal Note

I became interested in marine life following my BSc in Zoology at the Cornwall Campus of the University of Exeter. I went on to do an MSc in Marine Ecosystem Management at the University of St Andrews and became a research assistant there after graduating. Opportunities arose to be involved in many projects focused on the Scottish Inshore Fisheries. This included a Marine Scotland research and evaluation of the social, economic and operational implications of a Creel Limitation Pilot, and later, anaesthesia for European lobsters. I have since been a Fleet Researcher for the Seafish Industry Authority and a research assistant at Nottingham Trent University. Previous lobster anaesthetic trials led me to Stirling to further investigate ways in which slaughter can be made more humane for lobsters, crabs and prawns. Outside of academia, I enjoy going to church, doing youth work, dog walking and playing the violin.

Rules of Life

University of Edinburgh, Centre for Regenerative Medicine

Project Title

Changing landscapes: uncovering the molecular mechanisms of spinal cord development and regeneration in the axolotl

Primary Supervisor

Dr Aida Rodrigo Albors

Project Summary

Spinal cord stem cells, or ependymal glia, retain neural stem cell capacity even in the adult animal. Axolotl spinal cord stem cells have the remarkable ability to unlock and access developmental programs in regeneration, allowing full re-growth of the spinal cord upon injury. This is largely in contrast to most other species, in particular mammals such as mouse and human, which fail to regenerate the injured spinal cord.

To advance our understanding of the underlying differences between regenerative and non-regenerative species, I want to study molecular, reprogramming, genetic and epigenetic mechanisms behind spinal cord development and regeneration. I aim to identify and perturb key signaling factors involved in spinal cord development and regeneration. In the long term, understanding which developmental programs are or are not deployed in regeneration will have a great impact on advancing new strategies for treatments of spinal cord injuries.

Personal Note

I was fascinated studying brain scans of bilingual and monolingual children for my school graduation paper (mostly because I grew up bilingually (Austrian/Croatian)) and this was the beginning of my interest in (neuro)biology.

During my undergraduate studies at the University of Vienna, I specialized in Microbiology. Working with the highly regenerative axolotl salamander at IMP, Vienna inspired me to enrol in the Master’s course Developmental Biology and Genetics. I am proud of my first-author manuscript that just got accepted in Sept 2024.

I played Cello and Piano for 14 years in a youth orchestra and hope to continue my passion in Edinburgh. Likewise for tennis, my favorite sport. Besides, I also enjoy skiing, volleyball, aerial silk and yoga. My exchange semester and a lot of travelling allowed me to connect to many people from various nations and I am looking forward to meeting my EASTBIO cohort.

University of Aberdeen

Project Title

The role of ubiquitin in opioid receptor function

Primary Supervisor

Dr James Hislop

Project Summary

My project focusses on deepening our understanding of the role of ubiquitin in opioid receptor function. Ubiquitin, a small protein (~8kDa) commonly associated with proteasomal degradation, also has diverse roles as a post-translational modification on GPCR lysine residues – promoting functions like endocytosis, signalling and lysosomal trafficking. Though most GPCRs share a high degree of homology, the function of ubiquitin seems to be unique to different receptors. For example, the β2 adrenoreceptor undergoes ligand-dependant ubiquitination that targets the protein for lysosomal destruction. And in contrast, the δ-opioid receptor (DOR) is efficiently trafficked to the lysosome in the absence of ubiquitination. Since GPCR’s, and opioid receptors more specifically, are extremely druggable better understanding how these processes unfold may offer novel opportunities in the control of adverse effects, tolerance and addiction.

Personal Note

Hi, my name is Peter! I grew up in quiet Norfolk on the east coast of the UK. I moved to London in 2021 to study Pharmacology at the University of East London, where I graduated with a First-Class degree. In my second year, I applied successfully for a funded placement opportunity at Queen Mary University of London. Where I gained hand-on molecular biology experience investigating the contributions of YIF1A mutations to mental health disorder aetiology. I was invited to continue the project on a voluntary basis whilst completing my studies at UEL, and subsequently hired as a research assistant in the summer of 2024. This leads me to now, where I am excited to say I have just moved to sunny Scotland to begin a PhD at the University of Aberdeen!

University of St Andrews

Project Title

Structural basis for innate immune suppression by Rift Valley fever phlebovirus

Primary Supervisor

Dr Uli Schwarz-Linek

Project Summary

Rift Valley fever virus (RVFV) causes a disease known as Rift Valley fever (RVF), which infects humans and livestock, and is transmitted through bites from infected mosquitoes. RVFV produces a protein called non-structural protein (NSs), which is able to bind to TFIIH, and this binding, through a yet unknown mechanism, suppresses the interferon response of innate immunity. My project will use an in situ structural technique, cryo-electron tomography, to observe the binding of NSs to TFIIH to gain more insight into how NSs works to suppress innate immunity, thus working towards the design of drugs and/or vaccines that target NSs.

University of Edinburgh

Project Title

How can snails help us understand memory formation?

Primary Supervisor

Dr Jelena Baranovic

Project Summary

John is using snail-derived Conotoxins to track the neuronal receptors, AMPARs, that mediate synaptic plasticity. His work incorporates peptide development and validation, neuronal tissue and cellular preparations, combined with super-resolution microscopy, to visualize architectures and requirements for the formation of individual synapses. He hopes that his work will be informative for both the behavioral and disease-context implications of synaptic organization.

Personal Note

John grew up seeing a lot of Dubai, Cairo, and Ottawa. John completed his B.Sc. and M.Sc. at the University of Ottawa, and has a background in transcriptional regulation and skeletal muscle adaptability. He has since then worked in Boston and Paris with the iGEM foundation, and briefly worked as a technician in an Algae biotechnology laboratory focusing on high-value terpenoid production. Most recently, John worked as a lab manager under the supervision of Pierre Magistretti in Jeddah, Saudi Arabia. There, John fell in love with the idea that neurons manage their energy use and signal transmission locally, meaning neuronal activity results from complex, small-scale decision-making that is not well understood. Outside of work, John enjoys going to the movies, badminton, and is an avid coffee lover.

University of Aberdeen

Project Title

Priming In Human Brain and in Language Models: EEG, eye-tracking and LLM study

Primary Supervisor

Dr Anastasia Klimovich-Gray

Project Summary

My project looks at the phenomenon of structural priming that occurs when a sentence with one syntactic structure facilitates processing of another sentence with the same structure. We aim to create a unique multidimensional dataset that will combine and align human and Large Language Models (LLMs) measures of language processing. Specifically we will compare human participants’ eye-tracking and cortical EEG responses during processing of structurally primed sentences to predictions generated by LLMs for the same linguistic input. In doing so, we test to what extent LLMs are plausible models of syntactic processing in humans, thereby impacting the development of future generations LLMs.

Personal Note

I graduated from Cardiff University with a BSc in Psychology and MSc in Neuroimaging. I have previously worked on Autism and ADHD research at King’s College London, and more recently, I have been involved in neuromuscular studies in developmental populations at the Great Ormond Street Institute of Child Health. Taking a new direction with my current research, I am excited to explore syntax processing in human brain and in Large Language Models. Outside of academia I enjoy ballet and contemporary dance, language learning and knitting.

University of Edinburgh

Project Title

What shapes leaves? The interaction of physiology, defence and escape in passionflower leaf optimisation.

Primary Supervisor

Prof. Andrew Hudson

Project Summary

My PhD project explores the leaf trait evolution in passionflower plants. Leaves, the primary food source for herbivores, are also the primary source of energy in most plants, turning light, water and carbon dioxide into chemical energy. The central function of leaves in plant life puts them under strong selection, with pressure to maximise physiological function in a plant’s habitat but also minimise loss through defence and escape, resulting from herbivore driven stresses. Whilst we understand that particular leaf traits are adaptions to the biotic and abiotic environment, we know very little of the interplay between selective forces on these. The project uses passionflowers (genus Passiflora) as a study system, because they show high diversity in leaf traits, a close interaction with a specialist group of herbivores (Heliconius butterflies, also known as passionflower vine butterflies) and large variation in their ecology.

Personal Note

Hi, my name is Rebecca, and I am originally from Germany, although I have lived in the UK for a signification portion of my adult life. I have taken a slightly unconventional journey into academia as I initially trained to become a horticulturist. My work in horticulture sparked my interest in botany and plant taxonomy, and as a result I completed my postgraduate MSc degree in the Biodiversity and Taxonomy of Plants at the University of Edinburgh. After completing my MSc degree, I worked as a researcher and in postgraduate education at the Royal Botanic Garden Edinburgh (RBGE). In my research role at RBGE I developed a great fascination with plant morphology and thanks to my EASTBIO DTP PhD project, focusing on leaf evolution, I am able to pursue this interest further whilst developing my research skills. Outside of academia, I enjoy running, hiking, travelling, or simply exploring the wonders of our world.

University of St Andrews

Project Title

Recollections and Reciprocity – The Interplay of Memory and Cooperation

Primary Supervisor

Dr Manon Schweinfurth

https://nifets.dev/

University of Dundee

Project Title

Computational Evolutionary Transcriptomics of Single Cells

Primary Supervisor

Dr Hajk-Georg Drost

Project Summary

Evolutionary transcriptomics is a method for quantifying the conservation of genes expressed through different stages of a biological process by tracing back their evolutionary origins. This approach has revealed a recurrent ""developmental hourglass"" motif across the major kingdoms of life, where genes are maximally conserved during mid-development, mirroring morphological observations in animal embryogenesis. This hints towards the ""age"" of a gene acting as a macro-evolutionary signature, which can inform how gene regulation is organised in complex multicellular structures, and how history constrains this organisation.

Motivated by these findings, the aim of my project is to adapt this framework to the single-cell resolution, with our process of interest being the development and differentiation of individual cells. By mapping the Waddington landscape back to evolutionary history, we intend to gain a more refined characterisation of cell identity and its deviations.

Personal Note

I'm originally from Romania. I studied Mathematics and Computer Science at the University of Oxford, pursuing all sorts of topics before finally committing to computational biology. For my final project I developed a statistical tool for multiple sequence alignments of proteins, built upon a probabilistic model of how the peptide backbone might ""twist"" throughout evolutionary time. While I had chosen this project out of pure mathematical curiosity, by the end of it all I had become more fond of the science we were trying to model in the first place. Hence why I'm really excited to be part of EastBio, surrounded by biologists brandishing their pipettes at me.

When I'm not hooked up to the mainframe, I climb rocks and I like to draw.

University of Dundee

Project Title

Expanding the research toolbox in the kinase field: Combining MALDI-TOF Mass Spectrometry and Kinase Inhibitor Profiling

Primary Supervisor

Dr Virginia De Cesare

Project Summary

The project centres on the innovative integration of Matrix-Assisted Laser Desorption/Ionization Time-of-Flight (MALDI-TOF) mass spectrometry with kinase inhibitor profiling. This approach seeks to enhance our understanding of kinase activities, which play crucial roles in cellular signalling and contribute to various disease pathways. By combining these advanced techniques, we aim to improve the characterization of kinase behaviours and their interactions with inhibitors. This integration not only aids in the identification of potential therapeutic targets but also offers insights into the regulatory mechanisms that govern cellular functions. Ultimately, this research has the potential to inform the development of targeted treatments for diseases associated with dysregulated kinase activities.

Personal Note

I am from Nigeria and hold a BSc in Biochemistry from Covenant University, Nigeria. I furthered my studies by earning an MSc in Biomedical and Molecular Sciences from the University of Dundee in 2023. During my master’s research project, I focused on investigating novel small-molecule inhibitors of the deubiquitinating enzyme USP-14, utilizing high-throughput MALDI-TOF mass spectrometry to assess the selectivity and potency of newly modified inhibitors.

In addition to my academic pursuits, I have gained diverse professional experience across various industries. I am passionate about community service and have actively participated in fundraising initiatives for individuals affected by infectious diseases, particularly HIV.

Outside of my academic and professional endeavours, I enjoy cooking, traveling, and creating digital content, which allows me to express my creativity and connect with others. These experiences have shaped my journey and continue to inspire my pursuits in the biomedical field.

University of St Andrews

Project Title

Noisy Eaters: Acoustic feeding cues as social information in socially-foraging fishes and crustaceans

Primary Supervisor

Dr Mike Webster

Project Summary

Animals use information from multiple sensory modalities to make decisions which are essential for survival (e.g., during foraging). This information can be socially transmitted from hetero- or conspecifics, either through direct communication or ‘eavesdropping’. Acoustic cues are particularly important in aquatic environments as sound travels relatively far and quickly in water. This project aims to identify the socially-transmitted acoustic cues to feeding used by crustaceans and fishes and uncover the (social) learning processes involved. A further aim is to investigate how these cues are used in a multisensory way alongside cues from other sensory modalities (e.g., vision), and how both natural soundscapes and anthropogenic noise pollution may impact these processes to alter foraging behaviours/success. This research aims to improve our understanding of how animals use socially-transmitted acoustic cues to find sources of food, providing insight into social learning processes, multisensory integration and the effects of anthropogenic noise pollution.

Personal Note

Originally from Newcastle-upon-Tyne, I have a research background in foraging and multisensory learning, having previously worked with starlings, bumblebees and humans at Newcastle and Durham University. During my PhD and beyond, I wish to explore the sensory ecology of animals, with a focus on how anthropogenic sensory pollution impacts animal behaviours. I am also highly interested in science communication and public engagement. Outside of my research and academic activities, I enjoy reading, cooking, hiking, and spending time with my friends and family.

University of Edinburgh

Project Title

How does the brain find the way: investigating the neural circuits underlining the sense of direction

Primary Supervisor

Prof. Emma Wood

X - @jaycetus

University of Aberdeen

Project Title

Evolvability in mammal morphology

Primary Supervisor

Dr Catherine Sheard

Project Summary

We aim to use modern statistical and phylogenetic techniques to trace the tempo of morphological evolution in mammals. A large dataset of various morphometric measurements from thousands of extant mammals has been collated for this purpose, and in future extinct species will be added to this dataset. Understanding evolutionary tempo will hopefully shine light on whether certain lineages exhibit greater evolvability through time.

Personal Note

Like many palaeontologists, I have been fascinated by fossils from a very young age and sought out a career that could pursue that passion. I completed my undergraduate degree in geology and palaeontology from the University of Birmingham in 2021 and immediately signed on to an evolution-focused PhD project which I hope to bring some palaeontological perspective to.

Outside academics, I enjoy hiking, films, video games and playing table top RPGs with friends. A night out at the pub or club is good too. I'm an avid traveller and want to spend as much time as I can exploring my home countries of Indonesia and Singapore.

University of St Andrews

Project Title

Bayesian networks for inferring neural information flow from neural imaging data

Primary Supervisor

Dr V Anne Smith

Project Summary

Neural information flow networks represent dynamic use of underlying anatomical paths in the brain; understanding how these networks differ across behaviours and individuals can shed light on how the brain generates behaviour and cognition. Current advances in live imaging and genetically encoded voltage and calcium indicators have led to a wealth of data, including ability to track activity in entire brains and central nervous systems at near single-cell resolution. We need methods to reveal neural information flow networks from this data. A promising method for this task is Bayesian network models. My project focuses on advancing Bayesian networks for voltage and calcium imaging data, using live imaging data from Drosophila larvae and simulated neuronal networks as testbeds for the ability of this methodology to uncover effective networks.

University of Edinburgh

Project Title

The Best of Both Worlds; Merging Biocatalysis with Organocatalysis.

Primary Supervisor

Prof. Dominic Campopiano

Project Summary

I will carry out research in the next four years revolving around organo and biocatalysis. Through protein engineering to rewrite enzymatic functions and to mimic functions of other rate limiting step proteins.

Personal Note

I began my scientific career with a focus on metal-catalyzed organic synthesis, eventually expanding my interests to biocatalysis and protein science during my time in Campopiano group. Subsequently, I joined the Helleday group and later CMM at Karolinska Institutet, Stockholm, Sweden, under the supervision of Prof. Maurice Michel, funded by EUbOPEN and University of Edinburgh, where I concentrated on ROS DNA damage repair pathways. Building on previous award-winning research on OGG1, I aimed to develop treatments for inflammation, neurodegeneration, and even cancer through the application of organo and biocatalysis. The results have already demonstrated great success in this exciting novel field of treatments. After Karolinska Institutet, I returned to the Campopiano group in Edinburgh to continue my research and PhD work.

This article was published on 2024-12-17

EastBio Student Cohort 2024

Clean Growth

Madita Lina Buch (she/her)

University of Edinburgh, Centre for Regenerative Medicine

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Olivia Gray

University of Edinburgh

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Yating Guo (she/her)

University of St Andrews

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Benedict Tan (he/him)

University of Edinburgh

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Crops and Soil

Eve Anthoney (she/her)

University of Edinburgh

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Bea Atkinson (she/her)

University of Dundee

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Dougal Clumpas (he/they)

University of Edinburgh, School of Chemistry

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Talent Mabambe (he/him)

University of Aberdeen

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Joshua Osagiede

SRUC

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Lauren Tribbeck (she/her)

University of Aberdeen

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Health

Zunaira Aman (she/her)

University of Edinburgh, IQB3

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Lara Dasar

University of Aberdeen

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Rosina Graham (she/her)

University of Edinburgh

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