ZYTHERA (enZYme THERApeutics), a research project led by a team of University of Edinburgh scientists, is engineering enzyme replacement therapies (ERTs) for lysosomal storage diseases (LSDs) using generative artificial intelligence (AI). The team has been awarded £74,600 in funding from Scotland’s national economic development agency, Scottish Enterprise. Image The ZYTHERA team is being led by Dr Giovanni Stracquadanio, Senior Lecturer in Synthetic Biology and co-director of the Edinburgh Genome Foundry (EGF), and Professor Susan Rosser, also co-director of EGF and Chair of Synthetic Biology in the School of Engineering, who developed the protein expression system. The technology was developed as part of Dr Stracquadanio’s £1.4 million UKRI EPSRC Fellowship, and draws on Professor Rosser’s pioneering expertise in mammalian synthetic biology and biologics manufacturing. Related Links School of Biological Sciences News This article was published on 2024-06-17
