Publications

Journal Articles

Burger MG, Doyle R, Lin JS, Barron AE, Moule MG. (2025) Targeting intracellular populations of Pseudomonas aeruginosa with peptide-mimetic therapies: individual efficacy and synergistic rescue of obsolete antibiotics. bioRxiv 2025.08.26.672426. doi: 10.1101/2025.08.26.672426

Moule MG**, Benjamin AB**, Burger ML, Herlan C, Lebedev M, Lin JS, Koster KJ, Wavare N, Adams LG, Bräse S, Barron AE, Cirillo JD. (2024) Peptide-mimetic treatment of Pseudomonas aeruginosa in a mouse model of respiratory infection. Commun Biol. 7(1):1033. PMID: 39174819 doi: 10.1038/s42003-024-06725-1 (** equal contribution)

DiNardo AR, Arditi M, Kamat AM, Koster KJ, Carrero S, Nishiguchi T, Lebedev M, Benjamin AB, Avalos P, Lozano M, Moule MG, McCune B, Herron B, Ladki M, Sheikh D, Spears M, Herrejon IA, Dodge C, Kumar S, Hutchison RW, Ofili TU, Opperman LA, Bernard JA, Lerner SP, Udeani G, Neal G, Netea MG, Cirillo JD. (2023) Bacillus Calmette-Guérin vaccination as defense against SARS-CoV-2 (BADAS): a randomized controlled trial to protect healthcare workers in the USA by enhanced trained immune responses. Trials. 24(1):636. PMID: 37794431 doi: 10.1186/s13063-023-07662-w

Benjamin AB**, Moule MG**, Didwania MK, Hardy J, Saenkham-Huntsinger P, Sule P, Nielsen JE, Lin JS, Contag CH, Barron AE, Cirillo JD. (2022) Efficacy of Cathelicidin-Mimetic Antimicrobial Peptoids Against Staphylococcus aureus. Microbiol Spectr. PMID: 35467395 doi: 10.1128/spectrum.00534-22 (** equal contribution)

Smith RJ, Moule MG, Leon PA, Iverson ET, Kolibaba TJ, Cirillo JD, Grunlan JC. (2021) Polyelectrolyte Complex that Minimizes Bacterial Adhesion to Polyester. Macromol. Mater. Eng. 306(12). doi: 10.1002/mame.202100579

Kassab G, Cheburkanov V, Willis J, Moule MG, Kurachi C, Yakovlev V, Cirillo JD, Bagnato VS. (2020) Safety and delivery efficiency of a photodynamic treatment of the lungs using indocyanine green and extracorporeal near infrared illumination. J Biophotonics. doi: 10.1002/jbio.202000176

Moule MG, Cirillo JD. (2020) Mycobacterium tuberculosis Dissemination Plays a Critical Role in Pathogenesis. Front. Cell. Infect. Microbiol. 10:65. doi: 10.3389/fcimb.2020.00065

Marshall LE, Nelson M, Davies CH, Whelan AO, Jenner DC, Moule MG, Denman C, Cuccui J, Atkins TP, Wren BW, Prior JL. (2018) An O-Antigen Glycoconjugate Vaccine Produced Using Protein Glycan Coupling Technology Is Protective in an Inhalational Rat Model of Tularemia. J Immunol Res. 2018:8087916. doi: 10.1155/2018/8087916

Smith RJ, Moule MG, Sule P, Smith T, Cirillo JD, Grunlan JC. (2017) Polyelectrolyte Multilayer Nanocoating Dramatically Reduces Bacterial Adhesion to Polyester Fabric. ACS Biomater Sci Eng. 3(8):1845-1852. doi: 10.1021/acsbiomaterials.7b00250

Moule MG, Spink N, Lim J, Willcocks S, Guerra-Assunção JA, Clark TG, Titball RW, Cuccui J, Wren BW. (2015) Characterization of new virulence factors involved in the growth and survival of Burkholderia pseudomallei. Infect Immun. 84(3):701-10. doi: 10.1128/IAI.01102-15

Moule MG, Hemsley CM, Seet Q, Guerra-Assunção JA, Lim J, Sarkar-Tyson M, Clark TG, Tan PB, Titball RW, Cuccui J, Wren BW. (2014) Genome-Wide Saturation Mutagenesis of Burkholderia pseudomallei K96243 Predicts Essential Genes and Novel Targets for Antimicrobial Development. MBio. 5(1). doi: 10.1128/mBio.00926-13

Wagley S, Hemsley C, Thomas R, Moule MG, Vanaporn M, Andreae C, Robinson M, Goldman S, Wren BW, Butler CS, Titball RW. (2014) The Twin Arginine Translocation system is essential for aerobic growth and full virulence of Burkholderia thailandensis. J Bacteriology. 196(2):407-16. doi: 10.1128/JB.01046-13

Cuccui J, Thomas RM, Moule MG, D'Elia RV, Laws TR, Mills DC, Williamson D, Atkins TP, Prior JL, Wren BW. (2013) Exploitation of bacterial N-linked glycosylation to develop a novel recombinant glycoconjugate vaccine against Francisella tularensis. Open Biology. 3(5):130002. doi: 10.1098/rsob.130002

Moule MG, Monck DM, Schneider DS. (2010) Reciprocal Analysis of Francisella novicida Infections of a Drosophila melanogaster Model Reveal Host-Pathogen Conflicts Mediated by Reactive Oxygen and imd-Regulated Innate Immune Response. PLoS Pathogens 6(8):e1001065. doi: 10.1371/journal.ppat.1001065

Schneider DS, Ayres JS, Brandt SM, Costa A, Dionne MS, Gordon MD, Mabery EM, Moule MG, Pham LN, Shirasu-Hiza MM. (2007) Drosophila eiger mutants are sensitive to extracellular pathogens. PLOS Pathogens 3(3):e41. doi: 10.1371/journal.ppat.0030041

Hunt AE, Moule MG, Fried M. (2006) The rat ARF protein is translated from two closely spaced ATG start codons and can transcriptionally activate p53 in the absence of p53 protein stabilization. Cell Cycle 5(12):1324-30. doi: 10.4161/cc.5.12.2817

Rodriguez-Viciana P, Collins CH, Moule MG, Fried M. (2006) Chromosomal instability at a mutational hotspot in polyoma middle T antigen affects its ability to activate the ARF-p53 tumor suppressor pathway. Oncogene 25(10):1452-62. doi: 10.1038/sj.onc.1209197

Moule MG, Collins CH, McCormick F, Fried M. (2004) Role for PP2A in ARF signaling to p53. Proc. Natl. Acad. Sci. USA 101(39):14063-6. doi: 10.1073/pnas.0405533101

Book Chapters

Sharan R, Galbadage T, Saenkham P, Moule MG, Sule P, Kong Y, Cirillo JD. (2019) Optical in vivo Imaging in Tuberculosis Research. In: Tuberculosis Host-Pathogen Interactions. Jeffrey D. Cirillo and Ying Kong (eds). Springer Nature Switzerland, pp. 155-200.

Cuccui J, Langdon RH, Moule MG, Wren BW. (2012) Bacterial N-linked Glycosylation Systems: Current Knowledge and Future Perspectives. In: Bacterial Glycomics: Current Research, Technology and Applications. S.M. Twine, A.N. Reid, Christopher W. Reid (eds). Norfolk, UK: Caister Academic Press, pp. 83-94.

Moule MG, Schneider DS. Drosophila Innate Immune Responses. In: Encyclopedia of Life Sciences. John Wiley and Sons Ltd, Chichester.