Dr Maddie Moule

Dr. Madeleine Moule is a Chancellor’s Fellow in Global Health at the University of Edinburgh. She earned her Ph.D. in Microbiology and Immunology from Stanford University where she studied the host-pathogen interactions of Francisella tularensis with the Drosophila innate immune system, and went on to expand her interest in bacterial respiratory pathogens through postdocs in Brendan Wren’s laboratory at the London School of Hygiene and Tropical Medicine, and at Texas A&M University on an NIH F32 fellowship. Her research examines bacterial host-pathogen interactions, combining the power of large-scale genetic screens with air-liquid interface (ALI) models to dissect the mechanisms of candidate virulence factors. She is particularly interested in understudied bacteria such as the tropical pathogen Burkholderia pseudomallei, underexplored aspects of pathogenesis such as the intracellular life of the extracellular pathogen Pseudomonas aeruginosa, and poorly understood bacterial variants such as cell wall-deficient L-forms.  

Academic bio:

• 1996-2000: B.A. Biology, Women’s Studies, Oberlin College, USA
• 2000-2004: Staff Research Associate II, Comprehensive Cancer Center, UCSF, USA (advised by Professor Mike Fried)
• 2004-2010: Ph.D, Microbiology and Immunology, Stanford University, USA (advised by Professor David Schneider)
• 2010-2014: NIH F32 Postdoctoral Fellow, Dept. of Pathogen Mol. Biol., London School of Hygiene and Tropical Medicine (advised by Professor Brendan Wren)
• 2014-2020: Postdoctoral Research Associate, Dept. of Microbial Path. and Immunology, Texas A&M University (advised by Professor Jeff Cirillo)
• 2020-present: Chancellor’s Fellow, School of Biological Sciences, University of Edinburgh