Genome stability and inheritance

Understanding the mechanism of chromosome segregation.

Mechanisms of chromosome segregation and genome stability.

Investigating the temporal dynamics of DNA replication and its role in epigenetic inheritance.

Structural biology of meiotic chromosome synapsis and recombination.

Mechanisms and regulation of chromosome replication.

Rebuilding nuclei into mitotic chromosomes.

Mechanisms for microcephaly, cancer and autoinflammation.

Systems biology of proteome dynamics.

Biophysical mechanisms of chromosome organisation and transcription.

Chromosome segregation in mitosis and meiosis.

Genetics of cilia biology.

The meiotic spindle and chromosomes in oocytes.

Mechanistic cell biology of cell division of somatic and germ cells in health and disease.

Genetic technologies to control proteins, cells and tissues.