Research

Read the outline of our research areas, divided into sections.

Section I

How do trypanosomes 'listen' to each other to enable their developmental progression to stumpy forms in the bloodstream?

Section II

  • How do trypanosomes know when to differentiate to the tsetse fly form: what molecules regulate the initiation of differentiation?

  • What prepares the trypanosome for uptake, survival and differentiation in the tsetse fly?

Section III

What governs the changes in the parasite during differentiation: which genes are regulated and how are they controlled?

Section IV

Once differentiation is complete, how is the differentiated state maintained?