Find details of our past meeting programs.
9.00-9.05 | Opening remarks |
Session One: cell divisionChair: Vladimir Volkov | |
9.10-9.30 | Nicolas Joly, IJM ParisCharacterization of Katanin's Microtubule Binding Domains unveils the critical role of its regulatory subunit (p80) for microtubule-severing activity |
9.30-9.50 | Viji Draviam, QMULOrderly recruitment of Ndc80-Nuf2 onto interphase microtubules promotes Astrin loading along microtubule walls |
9.50-10.10 | Gerard Pieper (Marston lab) University of EdinburghA weak spindle assembly checkpoint can explain the error-prone first mitosis of human embryos |
10.10-10.30 | Isabel Leitch (Gruneberg Lab), University of OxfordUsing the dTag system for rapid targeted protein degradation to investigate the role of PP1 in mitosis |
10.30-11.00 | Coffee |
11.00-11.30 | Posters |
Session Two: CiliaChair: Jose Ferreira | |
11.30-11.50 | Atlanta Cook, University of EdinburghLarge-scale interaction analysis and modelling of Trypanosoma brucei flagellar dynein networks reveals novel interacting factors |
11.50-12.10 | Sam Lacey, (Pigino lab) MilanGlobal rearrangement of retrograde intraflagellar transport trains underpins bidirectional transport in cilia |
12.10-12.30 | Elisa Vitiello, (Gergely lab) University of OxfordCAPture - a new method to unravel centrosome composition -identifies RNA binding proteins |
12.30-13.00 | Paul Guichard, University of Geneva, EMBO YIP lectureTime series reconstruction of centriolar assembly using ultrastructure expansion microscopy |
13.00-13.45 | Lunch |
13.30-14.30 | Poster |
Session Three: TransportChair: Clinton Lau
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14.30-14.50 | Girish Mali, University of OxfordDNAAF9/Shulin and ARL3 promote ciliary outer arm dynein trafficking and activation |
14.50-15.10 | Ammaar Saeed (Carter lab), MRC-LMBJIP1, JIP3, and KLC1 tether a dynein/kinesin super-complex |
15.10-15.30 | Lucas Albacete (Bullock lab), MRC-LMBOxidative stress drives dynein-dependent relocation of multiple membraneous organelles |
15.30-15.50 | Astrid Bostrom, (Allan lab), University of ManchesterUsing a kinesin-1 auxin-inducible degron system to investigate cargo transport in C. elegans |
15.50-15.55 | Lumicks |
16.00-16.45 | Coffee |
Session Four: Microtubules and MIPsChair: Natalia Bulgakova | |
16.45-17.05 | Lee-Ya Chu, (Molodstov lab) Crick InstituteForce-transducing molecular ensembles at growing microtubule tips control mitotic spindle size |
17.05-17.25 | Jessica Cross, (Dodding lab) University of BristolAllosteric regulation of a microtubule motor through de novo protein design |
17.25-17.45 | David Keays, University of CambridgeThe role of EB2 in neurodevelopment and disease |
17.45 | Concluding remarks and poster prizes |
9.00 | Opening remarks |
9.05 | Sponsors |
Session One: MitosisChair: Bungo Akiyoshi | |
9.10-9.30 | Dionn Hargreaves (Woolner Lab), University of ManchesterMitotic Spindle dynamics in stretched epithelial tissue in vivo and in silico |
9.30-9.50 | Francois Nedelec, University of CambridgeA Model of Spindle Assembly in Plant Roots |
9.50-10.10 | Nooshin Sheidaei (Tanaka Lab), University of DundeeSpatial regulation of kinetochore with the mitotic spindle interaction by perinuclear acto-myosin network contraction in early mitosis |
10.10-10.30 | Nooshin Sheidaei (Tanaka Lab), University of DundeeSpatial regulation of kinetochore with the mitotic spindle interaction by perinuclear acto-myosin network contraction in early mitosis |
10.30-11.00 | Coffee break |
11.00-11.30 | Posters |
Session Two: CiliaChair: Viki Allan | |
11.30-11.50 | Aakash Mukhopadhyay (Roberts Lab), Birkbeck UOLIFT-A structure reveals carriages for membrane protein transport into cilia |
11.50-12.10 | Helen Foster (Pigino Lab), Human Technopole, MilanCryo-electron tomography shows FAP256/Cep104 is a master controller of ciliary tip ultrastructure |
12.10-12.30 | Daniel O Dodd (Mill Lab), University of EdinburghTUBB4B, a beta tubulin isotype with essential roles in mammalian motile cilia |
12.30-12.50 | Dominika Kwecka (Philip Lab), University of EdinburghProtein Kinase A regulates axoneme stability during transmission of malaria parasites |
12.50-13.20 | Lunch |
13.20-14.30 | Posters |
Session Three: MotorsChair: Claire Friel | |
14.30-14.50 | Charlotte Aumeier, University of GenevaRunning kinesin-1 shapes the microtubule acetylation gradient |
14.50-15.10 | Ferdos Abid Ali (Carter Lab), MRC-LMBKIF1C activates dynein by relieving FHF cargo adaptor autoinhibition |
15.10-15.30 | Alice Bittleston (Derivery Lab), MRC-LMBHow a two amino acid deletion can break polarized trafficking of fate determinants: Insights from structural and functional studies of an uncharacterized kinesin mutant. |
15.30-15.50 | Dhanya Cheerambathur, University of EdinburghRepurposing the Chromosome-Microtubule Coupling Machinery for Dendrite Branching |
15.50-16.50 | Coffee and posters |
Session Four: Microtubule dynamicsChair: Joe Atherton | |
16.50-17.10 | Hermes Gadelha, University of BristolThe surprising mechanics of microtubules |
17.10-17.30 | Sam Wallis (Godinho Lab), Barts Cancer Institute, QMULRegulation of microtubule acetylation during the DNA damage response promotes efficient repair |
17.30-17.50 | Beth Lawrence (Zanic Lab), Vanderbilt UniversityCLASPs stabilize the intermediate state between microtubule growth and catastrophe |
17.50 | Closing remarks |
The program and speakers are listed below. Poster title and presenters will be sent out to participants.
9.00 | Opening remarks |
Session One: Cell divisionChair: Dhanya Cheerambathur | |
9.10-9.30 | Daniel Hayward, University of OxfordMPS1 regulation at the kinetochore |
9.30-9.50 | Nawseen Tarannum, University of ManchesterMechanical regulation of cell division orientation: investigating the role of NuMA |
9.50-10.10 | Xinhong Song, Queen Mary University of LondonCells protect chromosome-microtubule attachments, independent of biorientation, using an Astrin-PP1 and Cyclin-B-Cdk1 feedback loop |
10.10-10.30 | Isaac Siu-Shing Wong, University of OxfordCo-existing liquid- and solid-like phases organize centrosomes |
10.30-11.00 | Coffee break |
11.00-11.30 | Posters |
Session Two: Motor and microtubule structureChair: Anthony Roberts | |
11.30-11.50 | Sami Chaaban, MRC Laboratory of Molecular BiologyStructure of dynein-dynactin on microtubules shows tandem recruitment of cargo adaptors |
11.50-12.10 | Mark Dodding, University of BristolMolecular architecture of the autoinhibited kinesin-1 lambda particle |
12.10-12.30 | Josie Ferreira, Birkbeck, University of LondonLuminal helices and microtubule giants revealed in the Plasmodium parasite |
12.30-12.50 | Vladimir Volkov, Queen Mary University of LondonElectron cryo-tomography reveals organisation of microtubule end-tracking protein assemblies |
12.50-13.20 | Lunch |
13.20-14.30 | Posters |
Session Three: Microtubules and diseasesChair: Girish Mali | |
14.30-14.50 | Amadeus Xu, Francis Crick InstituteKinesin-1 drives motility of intracellular mature virions during Vaccinia infection and in vitro |
14.50-15.10 | Kriti Gupta, University of LiverpoolNeuronal ageing: the roles and regulation of microtubules |
15.10-15.30 | Anne Straube, University of WarwickForce generation of KIF1C and its impairment by pathogenic mutations |
15.30-15.50 | Jovana Deretic, Koç University, TurkeyCiliopathy-linked protein, CCDC66, regulates microtubule stability to promote cilia formation and timely mitotic progression |
15.50-16.50 | Coffee and posters |
Session Four: Motor and microtubule regulationChair: Emmanuel Derivery | |
16.50-17.10 | Benjamin Craske, University of EdinburghCENP-E and PRC1 cooperate to organise microtubule bundles |
17.10-17.30 | Yean Ming Chew, University of WarwickTaxol affects different metazoan microtubules differently |
17.30-17.50 | Evelyn Smith, University of SheffieldDevelopment and optimisation of a new single molecule assay to study kinesin-1 activation |
17.50 | Closing remarks |
18.00 | End |
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