Publications

Latest publications from the lab.

2022

Stirpe, A., and Heun, P. (2022). The ins and outs of CENP-A: Chromatin dynamics of the centromere-specific histone. Semin Cell Dev Biol. 10.1016/j.semcdb.2022.04.003. 

2020

Bobkov, G.O.M., Huang, A., van den Berg, S.J.W., Mitra, S., Anselm, E., Lazou, V., Schunter, S., Feederle, R., Imhof, A., Lusser, A., Jansen, L.E.T., and Heun, P. (2020). Spt6 is a maintenance factor for centromeric CENP-A. Nature communications 11, 2919. 

Medina-Pritchard, B., Lazou, V., Zou, J., Byron, O., Abad, M.A., Rappsilber, J., Heun, P., and Jeyaprakash, A.A. (2020). Structural basis for centromere maintenance by Drosophila CENP-A chaperone CAL1. EMBO J 39, e103234. PMC7110144 

Scacchetti, A., Schauer, T., Reim, A., Apostolou, Z., Campos Sparr, A., Krause, S., Heun, P., Wierer, M., & Becker, P. B. (2020). Drosophila SWR1 and NuA4 complexes are defined by DOMINO isoforms. eLife, 9, e56325.https://doi.org/10.7554/eLife.56325. PMID: 32432549; PMCID: PMC7239659. 

2019

Roure, V., Medina-Pritchard, B., Anselm, E., Jeyaprakash, A.A., and Heun, P. (2019). Reconstituting Drosophila centromere identity in human cells. Cell reports, 2019 Oct 8;29(2):464-479.e5. doi: 10.1016/j.celrep.2019.08.067.

Logsdon GA, Gambogi CW, Liskovykh MA, Barrey EJ, Larionov V, Miga KH, Heun P., Black BE., Human Artificial Chromosomes that Bypass Centromeric DNA. Cell. 2019 Jul 25;178(3):624-639.e19. doi: 10.1016/j.cell.2019.06.006. 

2018

Kyriacou, E. and P. Heun, High-resolution mapping of centromeric protein association using APEX-chromatin fibers. Epigenetics Chromatin, 2018. 11(1): p. 68. 

Bobkov, G.O.M., N. Gilbert, and P. Heun, Centromere transcription allows CENP-A to transit from chromatin association to stable incorporation. J Cell Biol, 2018. 217(6): p. 1957-1972. 

Anselm, E., et al., Oligomerization of Drosophila Nucleoplasmin-Like Protein is required for its centromere localization. Nucleic Acids Res, 2018. 46(21): p. 11274-11286. 

2017

Barrey, E.J. and P. Heun, Artificial Chromosomes and Strategies to Initiate Epigenetic Centromere Establishment. Prog Mol Subcell Biol, 2017. 56: p. 193-212. 

2015

Logsdon, G.A., et al., Both tails and the centromere targeting domain of CENP-A are required for centromere establishment. J Cell Biol, 2015. 208(5): p. 521-31. 

2014

Padeken, J. and P. Heun, Nucleolus and nuclear periphery: velcro for heterochromatin. Curr Opin Cell Biol, 2014. 28: p. 54-60.
Barth, T.K., et al., Identification of novel Drosophila centromere-associated proteins. Proteomics, 2014. 14(19): p. 2167-78.

2013

Thomae, A.W., et al., A pair of centromeric proteins mediates reproductive isolation in Drosophila species. Dev Cell, 2013.27(4): p. 412-24.
Padeken, J., et al., The nucleoplasmin homolog NLP mediates centromere clustering and anchoring to the nucleolus. Molecular cell, 2013. 50(2): p. 236-49.

2011

Olszak, A.M., et al., Heterochromatin boundaries are hotspots for de novo kinetochore formation. Nature cell biology, 2011.13(7): p. 799-808.
Mendiburo, M.J., et al., Drosophila CENH3 is sufficient for centromere formation. Science, 2011. 334(6056): p. 686-90.