| Julian Ng-Kee-Kwong, Ben Philps, Fiona N. C. Smith, Aleksandra Sobieska, Naiming Chen, Constance Alabert, Hakan Bilen & Sara C. B. Buonomo (2025) Supervised and unsupervised deep learning-based approaches for studying DNA replication spatiotemporal dynamics. Commun Biol 26, 311. doi.org/10.1038/s42003-025-07744-2 |
| Forte G., Buonomo S, Cook P. R., Gilbert N., Marenduzzo, D. and Orlandini E. (2025) Modelling the 3D spatiotemporal organisation of chromatin replication. PRX Life 2, 3, 033014 doi.org/10.1103/PRXLife.2.033014 |
| Malzl, D., Peycheva, M., Rahjouei, A., Gnan, S., Klein, K. N., Nazarova, M., Schoeberl, U. E., Gilbert, D. M., Buonomo, S. C. B., Di Virgilio, M. et al. RIF1 regulates early replication timing in murine B cells. Nat Commun14, 8049, (2023). |
| Naiming Chen & Sara C.B. Buonomo (2023) Three-dimensional nuclear organisation and the DNA replication timing program. Curr. Op. Struct. Biol 2023 Dec:83:102704. doi: 10.1016/j.sbi.2023.102704. Epub 2023 Sep 21. |
| *Elin Enervald, Lynn Marie Powell, Lora Boteva, Rossana Foti, Nerea Blanes Ruiz, Gözde Kibar, Agnieszka Piszczek, Fatima Cavaleri, Martin Vingron, Andrea Cerase and Sara B.C. Buonomo (2021) RIF1 and KAP1 differentially regulate the choice of inactive versus active X chromosomes EMBO J. 40: e105865. |
| *Stefano Gnan, Ilya M. Flyamer, Kyle N. Klein, Eleonora Castelli, Jesse L. Turner, Patrick Weber, Andreas Maiser, Elin Enervald, Cristina M. Cardoso, Wendy A. Bickmore, David M. Gilbert and Sara C. B. Buonomo (2021) Nuclear organisation and replication timing are coupled through RIF1-PP1 interaction, Nat. Comm. 12: 2910 |
| Sara BC Buonomo Rif1-dependent regulation of genome replication in mammals, chapter in “DNA replication: From Old Principles to New Discovery”, in “Advances in Experimental Medicine and Biology”, Springer, (2017) 1042: 259-272. |
| Rasa Sukackaite, Daniela Cornacchia, MaleneRingkjøbing Jensen, Philippe Mas, Elin Enervald, Martin Blackledge, Darren J. Hart, Sara B.C. Buonomo (2017) Mouse Rif1 is a regulatory subunit of protein phosphatase 1 (PP1), Sci. Rep. 7: 2119. |
| Rossana Foti, Stefano Gnan, Daniela Cornacchia, Vishnu Dileep, Aydan Bulut-Karslioglu, Sarah Diehl, Andreas Buness, Felix A. Klein, Wolfgang Huber, Ewan Johnstone, Remco Loos, Paul Bertone, David M. Gilbert, Thomas Manke,Thomas Jenuwein and Sara B.C. Buonomo (2016) Nuclear architecture organized by Rif1 underpins the replication-timing program, Mol. Cell 61, pp. 260-273, -RESEARCH HIGHLIGHT in Nature Reviews Mol. Cell Biol. 17, doi:10.1038/nrm.2016.2. |
| Rasa Sukackaite, MaleneRingkjøbing Jensen, Philippe Mas, Martin Blackledge, Sara B.C. Buonomo$, Darren J. Hart$ (2014) Characterization of Rif1 structure-specific DNA binding domain by library-based construct screening, JBC 289, pp. 13903-11 ($ co-corresponding authors. I have been the main originator.) |
| Zimmermann M, Lottersberger F, Buonomo S.B., Sfeir A, de Lange T. (2013) 53BP1 regulates DSB repair using Rif1 to control 5' end resection Science 339, pp. 700-704 |
| *Daniela Cornacchia, Vishnu Dileep, Jean-Pierre Quivy, Rossana Foti, Federico Tili, Rachel Santarella-Mellwig, Claude Anthony, Genevieve Almouzni, David Gilbert and Sara B.C. Buonomo (2012) Mouse Rif1 is a key regulator of the replication-timing program in mammalian cells EMBO J., 31, pp. 3678-3690. RESEARCH HIGHLIGHT-HAVE YOU SEEN in EMBO J. 31, 3650-3652. |
| Sara B.C. Buonomo (2010) Heterochromatin DNA replication and Rif1 Experimental Cell research, 316, pp. 1907-13. |
| Sara B.C. Buonomo$, Yipin Wu, David Ferguson, Titia de Lange (2009) Mouse Rif1 helps homologous recombination at stalled replication forks J.Cell Biol. 187, pp. 385-98 ($ first and corresponding author.) |
| Silverman J, Takai H, Buonomo S.B., Eisenhaber F, de Lange T. (2004) Human Rif1, ortholog of a yeast telomeric protein, is regulated by ATM and 53BP1 and functions in the S-phase checkpoint. Genes Dev. 18, pp. 2108-2119. |
| Sara B.C. Buonomo, Kirsten P. Rabitsch, Jorg Fuchs, Stephan Gruber, Matt Sullivan, Frank Uhlmann, Mark Petronczki, Attila Toth and Kim Nasmyth. (2003) Division of the nucleolus and its release of Cdc14 during anaphase of meiosis I depends on Separase, Spo12 and Slk19. Dev. Cell 4, pp. 727-739. |
| Attila Toth, Kirsten P. Rabitsch, Marta Galova, Alexander Schleiffer, Sara B.C. Buonomo, Kim Nasmyth. (2000) Functional genomics identifies Monopolin a kinetochore protein required for segregation of homologs during meiosis I. Cell 103, pp. 1155-1168. |
| Sara B.C. Buonomo, Rosemary K. Clyne, Jorg Fuchs, Josef Loidl, Frank Uhlmann, Kim Nasmyth. (2000) Disjunction of homologous chromosomes in meiosis I depends on proteolytic cleavage of the meiotic cohesin Rec8 by separin. Cell 103, pp. 387-98. |
| Franz Klein, Peter Mahr, Marta Galova, Sara B.C. Buonomo, Christine Michaelis, Knud Nairz and Kim Nasmyth. (1999) A central role for cohesins in sister chromatid cohesion, formation of axial elements, and recombination during yeast meiosis. Cell 98, pp. 91-103. |
| Isabel Gonzalez, Sara B.C. Buonomo, Kim Nasmyth & Uwe von Ahsen. (1999) ASH1 mRNA localisation in yeast involves multiple secondary structural elements and Ash1 protein translation. Current Biology 9, pp. 337-340. |
| Sara B.C. Buonomo, Alessandro Michienzi, Fernanda G. De Angelis and Irene Bozzoni. (1999) The Rev protein is able to transport to the cytoplasm small nucleolar RNAs containing a Rev binding element. RNA 5, pp. 993-1002. |
| Silvia Prislei, Sara B. C. Buonomo, Alessandro Michienzi and Irene Bozzoni. (1997) Use of adenoviral VAI small RNA as a carrier for cytoplasmic delivery of ribozymes. RNA 3, pp. 1-11. |
