Publications

See below the recent publications from the lab.

2020s

A biocompatible Lossen rearrangement in Escherichia coli.  Nick W. Johnson, Marcos Valenzuela-Ortega, Thomas W. Thorpe, Yuta Era, Annemette Kjeldsen, Keith Mulholland, Stephen Wallace* Nature Chemistry 17, 1020–1026 (2025)

Microbially Derived P-S and P-Se Bond Formation. Connor L. Trotter, Yuta Era, Rory Gordon, Samantha Law, Christopher H. Switzer, Stephen Wallace*, JACS Au 2025 5(4), 2027-2032

Cultivating the future leaders of chemical biology. Anna Rulka, Elizabeth Adams, Akane Kawamura, Stephen Wallace*, RSC Chem. Biol. 2024, Advance Article

Redesigning microbial enzymes for sustainable chemical synthesis. J. F. C. Steele, S. Wallace*, Chem. Catal. 2024, 4, 8, 101087- 

Deciding the Future of Adipic Acid. J. F. C. Steele, S. Wallace*, Nat. Chem. 2024, 16, 838 

Microbial Upcycling of Waste PET to Adipic Acid. M. Valenzuela-Ortega, J. T. Suitor, M. F. M. White, T. Hinchcliffe, S. Wallace*, ACS Cent. Sci. 2023, 9, 11, 2057–2063

Biocompatible a-Methylenation of Metabolic Butyraldehyde in Living Bacteria. J. A. Dennis, N. W. Johnson, T. W. Thorpe, S. Wallace*, Angew. Chem. Int. Ed. 2023, 135, 38, e202306347 

Overproduction of Native and Click-able Colanic Acid Slime from Engineered Escherichia coli. J. C. Sadler, R. C. Brewster, A. Kjeldsen, A. F. González, J. S. Nirkko, S. Varzandeh, S. Wallace*, JACS Au 2023, 3, 2, 378–383

Engineering Biology for Sustainable 1,4-Butanediol Synthesis. C. L. Trotter, G. S. Babu, S. Wallace*, Trends Biotechnol. 2023

A New PETase from the Human Saliva Metagenome and Its Functional Modification via Genetic Code Expansion in Bacteria. M. F. M. White, S. Wallace*, Angew. Chem. Int. Ed. 2023, 62, 12, e202216963

Bread Waste - A Potential Feedstock for Sustainable Circular Biorefineries. V. Kumar*, P. Brancoli, V. Narisetty, S. Wallace, D. Charalampopoulos, B. K. Dubey, G. Kumar, A. Bhatnagar, S. K. Bhatia, M. J. Taherzadeh, Bioresour. Technol. 2022, DOI: org/10.1016/j.biortech.2022.128449 

Palladium Nanoparticles from Desulfovibrio alaskensis G20 Catalyze Biocompatible Sonogashira and Biohydrogenation Cascades. Y. Era, J. A. Dennis, L. E. Horsfall*, S. Wallace*, JACS Au 2022, 2, 11, 2446–2452 

Tyramine Derivatives Catalyze the Aldol Dimerization of Butyraldehyde in the Presence of Escherichia coli. J. A. Dennis, J. C. Sadler, S. Wallace*, ChemBioChem. 2022, e202200238 

Micellar Catalysis of the Suzuki Miyaura Reaction using Biogenic Pd Nanoparticles from Desulfovibrio alaskensis. Y. Era, J. A. Dennis, L. E. Horsfall*, S. Wallace*, Green Chem. 2021, 23, 8886–8890

Microbial Synthesis of Vanillin from Waste poly(ethylene terephthalate). J. C. Sadler, S. Wallace*, Green Chem. 2021, 23, 4665–4672 

Interfacing Non-Enzymatic Catalysis with Living Microorganisms. J. C. Sadler, J. A. Dennis, N. W. Johnson, S. Wallace*, RSC Chem. Biol. 2021, 2, 1073–1083

Optimizing the Biosynthesis of Oxygenated and Acylated Taxol Precursors in Saccharomyces cerevisiae using Advanced Bioprocessing Strategies. L. E. Walls, K. Malci, B. Nowrouzi, R. A. Li, L. d'Espaux, J. Wong, J. A. Dennis, A. J. C. Semiao, S. Wallace, J. L. Martinez, J. D. Keasling, L. Rios-Solis, Biotechnol. Bioeng. 2020, 118, 279–293

One-Pot Synthesis of Adipic Acid from Guaiacol in Escherichia coli. J. T. Suitor, S. Varzandeh, S. Wallace*, ACS Synth. Biol. 2020, 9, 2472–2476

Transition Metal-Free Reduction of Activated Alkenes Using a Living Microorganism. R. C. Brewster, J. T. Suitor, A. W. Bennett, S. Wallace*, Angew. Chem. Int. Ed. 2019, 58, 12409–12414

Synthetic Methodologies in Chemical Biology. In book: Biomolecular and Bioanalytical Techniques: Theory, Methodology and Applications. R. C. Brewster, S. Wallace*. John Wiley & Sons, Inc. Editor: V. Ramesh, 2019, ISBN: 9781119483977

Computationally Guided Discovery of a Reactive, Hydrophilic trans-5-Oxocene Dienophile for Bioorthogonal Labeling. W. D Lambert, S. L. Scinto, O. Dmittrenko, S. J. Boyd, R. A. Mehl, J. W. Chin*, J. M. Fox*, S. Wallace*, Org. Biomol. Chem. 2017, 15, 6640–6644 

Protein Modification via Alkyne Hydrosilylation Using a Substoichiometric Amount of Ruthenium(II) Catalyst. T. T. L. Kwan, O. Boutureira, E. C. Frye, S. J. Walsh, M. K. Gupta, S. Wallace, Y. Wu, F. Zhang, H. F. Sore, W. R. J. D. Galloway, J. W. Chin, M. Welch, G. J. L. Bernardes, D. R. Spring, Chem. Sci. 2017, 8, 3871–3878 

Interfacing Biocompatible Reactions with Engineered Escherichia coli. S. Wallace, E. P. Balskus, Methods Mol. Biol. 2017, 1586, 409–421

Designer Micelles Accelerate Flux Through Engineered Metabolism and Support Biocompatible Chemistry. S. Wallace, E. P. Balskus, Angew. Chem. Int. Ed. 2016, 55, 6023–6027 

Interfacing Microbial Styrene Production with a Biocompatible Cyclopropanation Reaction. S. Wallace, E. P. Balskus, Angew. Chem. Int. Ed. 2015, 54, 7106–7109

Using Non-Enzymatic Chemistry to Influence Microbial Metabolism. S. Wallace, E. E. Shultz, E. P. Balskus, Curr. Opin. Chem. Biol. 2015, 25, 71–79 

Opportunities for Merging Chemical and Biological Synthesis. S. Wallace, E. P. Balskus, Curr. Opin. Biotechnol. 2014, 30, 1–8 

Strain-Promoted Sydnone Bicyclo-[6.1.0]-nonyne Cycloaddition. S. Wallace, J.  W. Chin, Chem. Sci. 2014, 5, 1742–1744

Conformationally Strained trans-Cyclooctene with Improved Stability and Excellent Reactivity in Tetrazine Ligation. A. Darko, S. Wallace, O. Dmitrenko, M. M. Machovina, R. A. Mehl, J. W. Chin, J. M. Fox, Chem. Sci. 2014, 5, 3770–3776

Optimized Orthogonal Translation of Unnatural Amino Acids Enables Spontaneous Protein Double-Labeling and FRET. K. Wang, A. Sachdeva, D. J. Cox, N. W. Wilf, S. Wallace, R. A. Mehl, J. W. Chin, Nat. Chem. 2014, 6, 393–403 

A Cascade Strategy Enables a Total Synthesis of (–)-Gephyrotoxin. S. Chu, S. Wallace, M. D. Smith, Angew. Chem. Int. Ed. 2014, 53, 13826–13829 

Genetic Encoding of Bicyclononynes and trans-Cyclooctenes for Site-Specific Protein Labeling in vitro and in Live Mammalian Cells. K. Lang, L. Davis, S. Wallace, M. Mahesh, D. J. Cox, M. L. Blackman, J. M. Fox, J. W. Chin, J. Am. Chem. Soc. 2012, 134, 10317–10320

Rapid Synthesis and Zebrafish Evaluation of a Phenanthridine-Based Small Molecule Library. L. R. Donaldson, S. Wallace, D. Haigh, E. E. Paton, A. N. Hulme, Org. Biomol. Chem. 2011, 9, 2233–2239

 


This article was published on