Publications

2025

Systematic mapping of small nucleolar RNA interactions in human cells

Dunn-Davies, H., Dudnakova, T., Langhendries, J.-L., Watkins, N., Lafontaine, D. L. J. & Tollervey, D., 22 Nov 2025, In: Rna biology. 22, 1, p. 1-22

Rapid remodeling of NTP levels enables immediate translational adaptation to energy stress in yeast

Bexley, K., Ristová, M., Sharma, S., Spanos, C., Chabes, A. & Tollervey, D., 2 Oct 2025, In: Molecular Cell. 85, 19, p. 3623-3639.e7 25 p.

The type 6 secretion system immunity protein RhsFI has been repurposed for small RNA regulation in pathogenic Escherichia coli

Zammit, T., Sy, B., Shchepachev, V., Mediati, D. G., Poudyal, P., Norris, D., Bang, S., Alquethamy, S., Wu, W., Ullah, A., McAteer, S., Rowell, K., Michie, K., Gally, D., Tollervey, D. & Tree, J., 12 Aug 2025, In: Nucleic Acids Research. 53, 14, p. 1-17 17 p.

Multiple mechanisms of termination modulate the dynamics of RNAPI transcription

Petfalski, E., Winz, M.-L., Grelewska-Nowotko, K., Turowski, T. W. & Tollervey, D., 25 Mar 2025, In: Cell Reports. 44, 3, 24 p., 115325.

RNA methyltransferase SPOUT1/CENP-32 links mitotic spindle organization with the neurodevelopmental disorder SpADMiSS

Dharmadhikari, A. V., Abad, M. A., Khan, S., Maroofian, R., Sands, T. T., Ullah, F., Samejima, I., Shen, Y., Wear, M. A., Moore, K. E., Kondakova, E., Mitina, N., Schaub, T., Lee, G. K., Umandap, C. H., Berger, S. M., Iglesias, A. D., Popp, B., Abou jamra, R. & Gabriel, H. & 62 others, , 17 Feb 2025, In: Nature Communications. 16, 1, 24 p., 1703.

The transcriptional and translational landscape of HCoV-OC43 infection

Bresson, S., Sani, E., Armatowska, A., Dixon, C. & Tollervey, D., 27 Jan 2025, In: PLoS Pathogens. 21, 1, 22 p., e1012831.

reCRAC: A Stringent Method for Precise Mapping of Protein–RNA Interactions in Yeast

Ristová, M., Shchepachev, V. & Tollervey, D., 2025, mRNA Decay: Methods and Protocols. Wery, M. (ed.). New York, NY: Humana Press, Vol. 2863. p. 225-251 27 p. (Methods in Molecular Biology; vol. 2863).

2024

Roles of SNORD115 and SNORD116 ncRNA clusters in neuronal differentiation

Helwak, A., Turowski, T., Spanos, C. & Tollervey, D., 30 Nov 2024, In: Nature Communications. 15, 1, 16 p., 10427 .

Control of endothelial cell function and arteriogenesis by MEG3:EZH2 epigenetic regulation of integrin expression

Dunn-Davies, H., Dudnakova, T., Nogara, A., Rodor, J., Thomas, A. C., Parish, E., Gautier, P., Meynert, A., Ulitsky, I., Madeddu, P., Caporali, A., Baker, A., Tollervey, D. & Mitić, T., 11 Jun 2024, In: Molecular Therapy - Nucleic Acids. 35, 2, 102173.

Improved detection and consistency of RNA-interacting proteomes using DIA SILAC

Tan, T. C. J., Spanos, C. & Tollervey, D., 28 Feb 2024, In: Nucleic Acids Research. 52, 4, p. e21 14 p., gkad1249.

2023

The conserved RNA-binding protein Seb1 promotes cotranscriptional ribosomal RNA processing by controlling RNA polymerase I progression

Duval, M., Yague-Sanz, C., Turowski, T. W., Petfalski, E., Tollervey, D. & Bachand, F., 1 Dec 2023, In: Nature Communications. 14, 1, 14 p., 3013.

A posttranscriptional pathway regulates cell wall mRNA expression in budding yeast

Bresson, S., Shchepachev, V. & Tollervey, D., 28 Mar 2023, In: Cell Reports. 42, 3, 28 p., 112184.

2022

The SPARC complex defines RNAPII promoters in Trypanosoma brucei

Staneva, D. P., Bresson, S., Auchynnikava, T., Spanos, C., Rappsilber, J., Jeyaprakash, A. A., Tollervey, D., Matthews, K. R. & Allshire, R. C., 28 Sept 2022, In: eLIFE. 11, 23 p., e83135.

The RNA-binding landscape of HAX1 protein indicates its involvement in translation and ribosome assembly

Balcerak, A., Macech-Klicka, E., Wakula, M., Tomecki, R., Goryca, K., Rydzanicz, M., Chmielarczyk, M., Szostakowska-Rodzos, M., Wisniewska, M., Lyczek, F., Helwak, A., Tollervey, D., Kudla, G. & Grzybowska, E. A., 20 Sept 2022, In: Cells. 11, 19, 22 p., 2943.

The dual nature of the nucleolus

Tartakoff, A., DiMario, P., Hurt, E., McStay, B., Panse, V. G. & Tollervey, D., 1 Sept 2022, In: Genes and Development. 36, 13-14, p. 765-769 5 p.

The RNA-binding landscape of HAX1 protein indicates its involvement in ribosome biogenesis and translation

Balcerak, A., Macech-Klicka, E., Wakula, M., Tomecki, R., Goryca, K., Rydzanicz, M., Chmielarczyk, M., Szostakowska-Rodzos, M., Wisniewska, M., Lyczek, F., Helwak, A., Tollervey, D., Kudla, G. & Grzybowska, E. A., 20 Jun 2022, Molecular Biology and Evolution, 30 p.

A disease-linked lncRNA mutation in RNase MRP inhibits ribosome synthesis

Robertson, N., Shchepachev, V., Wright, D., Turowski, T. W., Spanos, C., Helwak, A., Zamoyska, R. & Tollervey, D., 3 Feb 2022, In: Nature Communications. 13, 1, 14 p., 649.

2021

Yeast Ssd1 is a non-enzymatic member of the RNase II family with an alternative RNA recognition interface

Bayne, R., Jayachandran, U., Kasprowicz, O., Bresson, S., Tollervey, D., Wallace, E. W. J. & Cook, A. G., 24 Jul 2021, In: Nucleic Acids Research. 15 p., gkab615.

NANOS2 is a sequence-specific mRNA-binding protein that promotes transcript degradation in spermatogonial stem cells

Codino, A., Turowski, T., Van De Lagemaat, L. N., Ivanova, I., Tavosanis, A., Much, C., Auchynnikava, T., Vasiliauskaitė, L., Morgan, M., Rappsilber, J., Allshire, R. C., Kranc, K. R., Tollervey, D. & O'carroll, D., 23 Jul 2021, In: iScience. 24, 7, p. 102762

2020

The expression of Rpb10, a small subunit common to RNA polymerases, is modulated by the R3H domain-containing Rbs1 protein and the Upf1 helicase

Cieśla, M., Turowski, T. W., Nowotny, M., Tollervey, D. & Boguta, M., 2 Dec 2020, In: Nucleic Acids Research. 48, 21, p. 12252-12268 17 p.

Stress-induced translation inhibition through rapid displacement of scanning initiation factors

Bresson, S., Shchepachev, V., Spanos, C., Turowski, T., Rappsilber, J. & Tollervey, D., 5 Nov 2020, In: Molecular Cell. 80, 3, p. 470-484.e8 15 p.

Integrative vectors for regulated expression of SARS-CoV-2 proteins implicated in RNA metabolism

Bresson, S., Robertson, N., Sani, E., Turowski, T. W., Shchepachev, V., Kompauerova, M., Spanos, C., Helwak, A. & Tollervey, D., 3 Nov 2020, In: Wellcome Open Research. 5, 261.

Nascent transcript folding plays a major role in determining RNA polymerase elongation rates

Turowski, T., Petfalski, E., Goddard, B. D., French, S. L., Helwak, A. & Tollervey, D., 6 Aug 2020, In: Molecular Cell. 79, 3, p. 488-503.e11

Substrate specificity of the TRAMP nuclear surveillance complexes

Delan-Forino, C., Spanos, C., Rappsilber, J. & Tollervey, D., 19 Jun 2020, In: Nature. 11, 3122.

Extended ncRNAs interfere with promoter nucleosome dynamics

Turowski, T. & Tollervey, D., 13 Jun 2020, In: Trends in Genetics.

High density of unrepaired genomic ribonucleotides leads to Topoisomerase 1-mediated severe growth defects in absence of ribonucleotide reductase

Cerritelli, S. M., Iranzo, J., Sharma, S., Chabes, A., Crouch, R. J., Tollervey, D. & El hage, A., 18 Mar 2020, In: Nucleic Acids Research. gkaa103.

Regulation of the RNAPII Pool Is Integral to the DNA Damage Response

Tufegdžić Vidaković, A., Mitter, R., Kelly, G. P., Neumann, M., Harreman, M., Rodríguez-Martínez, M., Herlihy, A., Weems, J. C., Boeing, S., Encheva, V., Gaul, L., Milligan, L., Tollervey, D., Conaway, R. C., Conaway, J. W., Snijders, A. P., Stewart, A. & Svejstrup, J. Q., 5 Mar 2020, In: Cell. 180, 6, p. 1245-1261.e21

Mapping exosome-substrate interactions in vivo by UV cross-linking

Delan-Forino, C. & Tollervey, D., 2020, The Eukaryotic RNA Exosome: Methods and Protocols. Springer Nature, Vol. 2062. p. 105-126 22 p. (Methods in molecular biology (Clifton, N.J.)).