Lab publications from 2024.
For a full list of publications, see Scholar
Opinion Article: Fly immunity comes of age: The utility of Drosophila as a model for studying variation in immunosenescence Corbally, M. K., & Regan, J. C. (2022) In: Frontiers in Aging, 108. DOI:https://doi.org/10.3389/fragi.2022.1016962
Long-lasting geroprotection from brief rapamycin treatment in early adulthood by persistently increased intestinal autophagy Juricic, P., et al. (2022) In: Nature Aging 2(9), 824-836. DOI:https://doi.org/10.1038/s43587-022-00278-w
Sexual identity of enterocytes regulates rapamycin-mediated intestinal homeostasis and lifespan extension Regan, J. C. & Lu, Y. X., et al. (2021) In: bioRvix DOI:https://doi.org/10.1101/2021.10.22.465415
A TORC1-histone axis regulates chromatin organisation and non-canonical induction of autophagy to ameliorate ageing Lu, Y. X., Regan, J. C., Eßer, J., et al. (2021) In: eLIFE 2021 May 14;10:e62233. DOI:https://doi.org/10.1371/journal.pgen.1009083
Fine-tuning autophagy maximises lifespan and is associated with changes in mitochondrial gene expression in Drosophila Bjedov I, Cochemé HM, Foley A, et al. (2020) In: PLOS Genetics DOI: https://doi.org/10.1371/journal.pgen.1009083
Lifespan Extension Via Dietary Restriction: Time to Reconsider the Evolutionary Mechanisms? Moatt, J.P., Savola, E., Regan, J.C. Nussey, D.H. and Walling, C.A. (2020) In: BioEssays DOI: https://doi.org/10.1002/bies.201900241
Sexual Dimorphism in Innate Immunity and Responses to Infection in Drosophila melanogaster Belmonte, R.L., Corbally, M., Duneau, D.F. and Regan, J.C. (2020) In: Frontiers in Immunology DOI: https://doi.org/10.3389/fimmu.2019.03075
Dietary restriction and insulin‐like signalling pathways as adaptive plasticity: A synthesis and re‐evaluation Regan, J.C., Froy, H., Walling, C.A., Moatt, J.P.,& Nussey, D.H. (2020) In: Functional Ecology DOI: https://doi.org/10.1111/1365-2435.13418
Ras inhibition by trametinib treatment in Drosophila attenuates gut pathology in females and extends lifespan in both sexes Regan, J.C., Lu, Y., Bolukbasi, E., Khericha, M., and Partridge, L. (2018) In: bioRxiv DOI: https://doi.org/10.1101/356295
Intestinal Fork Head Regulates Nutrient Absorption and Promotes Longevity Bolukbasi, E., Khericha, M., Regan, J.C. et al. (2017) In: Cell Reports, vol. 21, no. 3, pp. 641-653 DOI: https://doi.org/10.1016/j.celrep.2017.09.042
Sex difference in pathology of the ageing gut mediates the greater response of female lifespan to dietary restriction Regan, J.C., Khericha, M., Dobson, A.J., Bolukbasi, E., Rattanavirotkul, N. and Partrigde, L. (2016) In: eLIFE, vol. 5 DOI: https://doi.org/10.7554/eLife.10956
Steroid hormone signaling is essential to regulate innate immune cells and fight bacterial infection in Drosophila Regan, J.C., Brandao, A.S., Leitao, A.B., Mantas Dias, A.R., Sucena, E. and Jacinto, A. (2013) In: PLOS Pathogens, vol. 9, no. 10 DOI: https://doi.org/10.1371/journal.ppat.1003720
Gender and longevity: why men die earlier than women - biological and experimental evidence Regan,J.C. and Partridge, L. (2013) In: Best practice & research. Clinical endocrinology & metabolism, vol. 27, no. 4, pp. 467-479 DOI: https://doi.org/10.1016/j.beem.2013.05.016
Drosophila Hemocyte Migration - in vivo Assay for Directional Cell Migration Moreira, C., Regan, J.C., Zaidman-Remy, A.,Jacinto, A. and Prag, S. (2011) In: Cell Migration, vol769, pp249-260 DOI: https://doi.org/10.1007/978-1-61779-207-6_17
The Drosophila larva as a tool to study gut associated macrophages: PI3K regulates a discrete population of hemocytes at the proventriculus Zaidman-Remy, A., Regan, J.C., Brandao, A.S. and Jacinto, A. (2011) In: Developmental and Comparative Immunology, vol. 36, no. 4 DOI: https://doi.org/10.1016/j.dci.2011.10.013
An Fgf8-dependent bistable cell migratory event establishes CNS asymmetry Regan, J.C., Concha, M.L., Raussigne, M.,Russel, C. and Wilson S.W. (2009) In: Neuron, vol. 61, no. 1, pp. 27-34 DOI: https://doi.org/10.1016/j.neuron.2008.11.030
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