Publications

2024

Comparison of CRISPR/Cas9 and Cas12a for gene editing in Chlamydomonas reinhardtii

Ferenczi, A., Fellbaum, M., Chew, Y. P., Kidner, C. & Molnar, A., Dec 2024, In: Algal Research. 84, 20 p., 103796.

2023

Plant chemical variation mediates soil bacterial community composition

Buchkowski, R. W., Benedek, K., Bálint, J., Molnár, A., Felföldi, T., Fazakas, C., Schmitz, O. J. & Balog, A., 13 Apr 2023, In: Scientific Reports. 13, 1, 7 p., 6088.

2022

Developing a robust in vivo hairy root system for assessing transgene expression and genome editing efficiency in papaya

Thi Huyen Hoang, T., Nguyen, N. H., Thi Nguyen, L., Bui, T. P., Le, N. T., Trong Dao, N., Monteiro, M., Pham, N. B., Molnar, A., Chu, H. H. & Do, P. T., 28 Nov 2022, In: Plant Cell, Tissue and Organ Culture. 7 p.

DNA methylation can alter CRISPR/Cas9 editing frequency and DNA repair outcome in a target-specific manner

Přibylová, A., Fischer, L., Pyott, D., Bassett, A. & Molnar, A., 1 Sept 2022, In: New Phytologist. 235, 6, p. 2285-2299 15 p.

Simultaneously induced mutations in eIF4E genes by CRISPR/Cas9 enhance PVY resistance in tobacco

Le, N. T., Tran, H. T., Bui, T. P., Nguyen, G. T., Van Nguyen, D., Ta, D. T., Trinh, D. D., Molnar, A., Pham, N. B., Chu, H. H. & Do, P. T., 26 Aug 2022, In: Scientific Reports. 12, 1, 11 p., 14627.

2021

Mechanistic and genetic basis of single-strand templated repair at Cas12a-induced DNA breaks in Chlamydomonas reinhardtii

Ferenczi, A., Chew, A., Kroll, E., von Koppenfels, C., Hudson, A. D. & Molnar, A., 19 Nov 2021, In: Nature Communications. 12, 12 p., 6751.

Temperature modulates virus-induced transcriptional gene silencing via secondary small RNAs

Fei, Y., Pyott, D. & Molnar, A., 29 Jun 2021, (E-pub ahead of print) In: New Phytologist. 16 p.

Cutin: Cutin-acid endo-transacylase (CCT), a cuticle-remodelling enzyme activity in the plant epidermis

Xin, A., Fei, Y., Molnar, A. & Fry, S. C., 24 Feb 2021, (E-pub ahead of print) In: Biochemical Journal. 478, 4, p. 777-798 21 p., BCJ20200835.

Non-perfectly matching small RNAs can induce stable and heritable epigenetic modifications and can be used as molecular markers to trace the origin and fate of silencing RNAs

Fei, Y., Nyiko, T. & Molnar, A., 1 Feb 2021, In: Nucleic Acids Research. 14 p., gkab023.

2020

Rapid, high efficiency virus-mediated mutant complementation and gene silencing in antirrhinum

Tan, Y., Bukys, A., Molnar, A. & Hudson, A. D., 27 Oct 2020, In: Plant Methods. 16, 145.

Homology-directed transgene-free gene editing in Chlamydomonas reinhardtii

Ferenczi, A. & Molnar, A., 1 Jul 2020, (E-pub ahead of print) CRISPR-Cas Methods . Springer, p. 237-252 (Springer Protocols Handbooks ).

Potential for gene editing in antiviral resistance

Pyott, D., Fei, Y. & Molnar, A., 5 Jun 2020, (E-pub ahead of print) In: Current Opinion in Virology. p. 47-52

Shared mutations in a novel glutaredoxin repressor of multicellular trichome fate underlie parallel evolution of Antirrhinum species

Tan, Y., Barnbrook, M., Wilson, Y., Molnar, A., Bukys, A. & Hudson, A., 20 Apr 2020, In: Current Biology. 30, 8, p. 1357-1366.E4 10 p.

Virus-induced gene silencing in Streptocarpus rexii (Gesneriaceae)

Nishii, K., Fei, Y., Hudson, A., Möller, M. & Molnar, A., 7 Mar 2020, (E-pub ahead of print) In: Molecular Biotechnology.

Light triggers the miRNA-biogenetic inconsistency for de-etiolated seedling survivability in Arabidopsis thaliana

Choi, S. W., Ryu, M. Y., Viczián, A., Jung, H. J., Kim, G. M., Arce, A. L., Achkar, N. P., Manavella, P., Dolde, U., Wenkel, S., Molnár, A., Nagy, F., Cho, S. K. & Yang, S. W., 2 Mar 2020, In: Molecular Plant. 13, 3, p. 431-445 15 p.

2019

Distinct roles of Argonaute in the green alga Chlamydomonas reveal evolutionary conserved mode of miRNA-mediated gene expression

Chung, B. Y. W., Valli, A., Deery, M. J., Navarro, F. J., Brown, K., Hnatova, S., Howard, J., Molnar, A. & Baulcombe, D. C., 31 Jul 2019, In: Scientific Reports. 9, 1, 11091.

2018

Gene Editing of Microalgae: Scientific Progress and Regulatory Challenges in Europe

Spicer, A. & Molnar, A., 6 Mar 2018, In: Biology. 7, 1, 13 p.

2017

Efficient targeted DNA editing and replacement in Chlamydomonas reinhardtii using Cpf1 ribonucleoproteins and single-stranded DNA

Ferenczi, A., Pyott, D. E., Xipnitou, A. & Molnar, A., 19 Dec 2017, In: Proceedings of the National Academy of Sciences (PNAS). 114, 51, p. 13567-13572 6 p.

Improved denaturation of small RNA duplexes and it's application for northern blotting

Harris, C. J., Baulcombe, D. C. & Molnar, A., 25 Apr 2017, (E-pub ahead of print) Microrna detection and target identification: Methods and protocols. Dalmay, T. (ed.). Humana Press, p. 1-6 6 p. (Methods in Molecular Biology; vol. 1580).

Reply Escaping a low-security prison

Oparka, K. & Molnar, A., Mar 2017, In: Plant Cell. 29, 3, p. 431 1 p.

2016

Lost in transit: Long-distance trafficking and phloem unloading of protein signals in arabidopsis homografts

Paultre, D. S. G., Gustin, M-P., Molnar, A. & Oparka, K. J., 10 Oct 2016, In: Plant Cell. 28, 9, p. 2016-2025 10 p.

Engineering of CRISPR/Cas9-mediated potyvirus resistance in transgene-free Arabidopsis plants

Pyott, D., Sheehan, E. & Molnar, A., 1 Oct 2016, In: Molecular Plant Pathology. 17, 8, p. 1276–1288 29 p.

Most microRNAs in the single-cell alga Chlamydomonas reinhardtii are produced by Dicer 2 like 3-mediated cleavage of introns and untranslated regions of coding RNAs

Valli, A., Santos, B. A. C. M., Hnatova, S., Bassett, A. R., Molnar, A., Chung, B. Y. & Baulcombe, D. C., 1 Apr 2016, In: Genome Research. 26, 4, p. 519-529 12 p.

Mobile small RNAs regulate genome-wide DNA methylation

Lewsey, M. G., Hardcastle, T. J., Melnyk, C. W., Molnar, A., Valli, A., Urich, M. A., Nery, J. R., Baulcombe, D. C. & Ecker, J. R., 9 Feb 2016, In: Proceedings of the National Academy of Sciences (PNAS). 113, 6, p. E801-810 10 p.

2015

FDF-PAGE: A powerful technique revealing previously undetected small RNAs sequestered by complementary transcripts

Harris, C. J., Molnar, A., Müller, S. Y. & Baulcombe, D. C., 27 May 2015, In: Nucleic Acids Research. 43, 15, p. 7590-7599 10 p.

Going mobile: Non-cell-autonomous small RNAs shape the genetic landscape of plants

Pyott, D. E. & Molnar, A., Apr 2015, In: Plant biotechnology journal. 13, 3, p. 306-318 13 p.

2014

5′ isomiR variation is of functional and evolutionary importance

Tan, G. C., Chan, E., Molnar, A., Sarkar, R., Alexieva, D., Isa, I. M., Robinson, S., Zhang, S., Ellis, P., Langford, C. F., Guillot, P. V., Chandrashekran, A., Fisk, N. M., Castellano, L., Meister, G., Winston, R. M., Cui, W., Baulcombe, D. & Dibb, N. J., 23 Jul 2014, In: Nucleic Acids Research. 42, 14, p. 9424-9435 12 p.

2013

Plant mobile small RNAs

Dunoyer, P., Melnyk, C., Molnar, A. & Slotkin, R. K., Jul 2013, In: Cold Spring Harbor perspectives in biology. 5, 7, 3 p., 017897.

2012

Artificial microRNA-mediated knockdown of pyruvate formate lyase (PFL1) provides evidence for an active 3-hydroxybutyrate production pathway in the green alga Chlamydomonas reinhardtii

Burgess, S. J., Tredwell, G., Molnar, A., Bundy, J. G. & Nixon, P. J., 30 Nov 2012, In: Journal of Biotechnology. 162, 1, p. 57-66 10 p.

A PHABULOSA/Cytokinin Feedback Loop Controls Root Growth in Arabidopsis

Dello Ioio, R., Galinha, C., Fletcher, A. G., Grigg, S. P., Molnar, A., Willemsen, V., Scheres, B., Sabatini, S., Baulcombe, D., Maini, P. K. & Tsiantis, M., 25 Sept 2012, In: Current Biology. 22, 18, p. 1699-1704 6 p.

2011

Mobile 24 nt small RNAs direct transcriptional gene silencing in the root meristems of Arabidopsis thaliana

Melnyk, C. W., Molnar, A., Bassett, A. & Baulcombe, D. C., 11 Oct 2011, In: Current Biology. 21, 19, p. 1678-1683 6 p.

Intercellular and systemic movement of RNA silencing signals

Melnyk, C. W., Molnar, A. & Baulcombe, D. C., 31 Aug 2011, In: EMBO Journal. 30, 17, p. 3553-3563 11 p.

The specific binding to 21-nt double-stranded RNAs is crucial for the anti-silencing activity of Cucumber vein yellowing virus P1b and perturbs endogenous small RNA populations

Valli, A., Carlos Oliveros, J., Molnar, A., Baulcombe, D. & Antonio Garcia, J., 30 Jun 2011, In: RNA. 17, 6, p. 1148-1158 11 p.

Silencing signals in plants: A long journey for small RNAs

Molnar, A., Melnyk, C. & Baulcombe, D. C., 11 Jan 2011, In: Genome Biology. 12, 1, 8 p., 215.

2010

RNA silencing of hydrogenase(-like) genes and investigation of their physiological roles in the green alga Chlamydomonas reinhardtii

Godman, J. E., Molnar, A., Baulcombe, D. C. & Balk, J., 1 Nov 2010, In: Biochemical Journal. 431, 3, p. 345-352 8 p.

Small silencing RNAs in plants are mobile and direct epigenetic modification in recipient cells

Molnar, A., Melnyk, C. W., Bassett, A., Hardcastle, T. J., Dunn, R. & Baulcombe, D. C., 14 May 2010, In: Science. 328, 5980, p. 872-875 4 p.

2009

Highly specific gene silencing by artificial microRNAs in the unicellular alga Chlamydomonas reinhardtii

Molnar, A., Bassett, A., Thuenemann, E., Schwach, F., Karkare, S., Ossowski, S., Weigel, D. & Baulcombe, D., Apr 2009, In: The Plant Journal. 58, 1, p. 165-174 10 p.

2007

miRNAs control gene expression in the single-cell alga Chlamydomonas reinhardtii

Molnar, A., Schwach, F., Studholme, D. J., Thuenemann, E. C. & Baulcombe, D. C., 28 Jun 2007, In: Nature. 447, 7148, p. 1126-U15 5 p.

2006

Defective RNA processing enhances RNA silencing and influences flowering of Arabidopsis

Herr, A. J., Molnar, A., Jones, A. & Baulcombe, D. C., 10 Oct 2006, In: Proceedings of the National Academy of Sciences (PNAS). 103, 41, p. 14994-15001 8 p.

Isolation and cloning of small RNAs from virus-infected plants

Chappell, L., Baulcombe, D. & Molnár, A., Jan 2006, In: Current protocols in microbiology. Chapter 16, p. Unit 16H.2

2005

Aureusvirus P14 is an efficient RNA silencing suppressor that binds double-stranded RNAs without size specificity

Merai, Z., Kerenyi, Z., Molnar, A., Barta, E., Valoczi, A., Bisztray, G., Havelda, Z., Burgyan, J. & Silhavy, D., Jun 2005, In: Journal of Virology. 79, 11, p. 7217-7226 10 p.

Plant virus-derived small interfering RNAs originate predominantly from highly structured single-stranded viral RNAs

Molnar, A., Csorba, T., Lakatos, L., Varallyay, E., Lacomme, C. & Burgyan, J., Jun 2005, In: Journal of Virology. 79, 12, p. 7812-7818 7 p.

2004

Crystal structure of p19 - a universal suppressor of RNA silencing

Baulcombe, DC. & Molnar, A., Jun 2004, In: Trends in biochemical sciences. 29, 6, p. 279-281 3 p.

2003

Low temperature inhibits RNA silencing-mediated defence by the control of siRNA generation

Szittya, G., Silhavy, D., Molnar, A., Havelda, Z., Lovas, A., Lakatos, L., Banfalvi, Z. & Burgyan, J., 3 Feb 2003, In: EMBO Journal. 22, 3, p. 633-640 8 p.

A viral protein suppresses RNA silencing and binds silencing-generated, 21-to 25-nucleotide double-stranded RNAs

Silhavy, D., Molnar, A., Lucioli, A., Szittya, G., Hornyik, C., Tavazza, M. & Burgyan, J., 17 Jun 2002, In: EMBO Journal. 21, 12, p. 3070-3080 11 p.

Short defective interfering RNAs of tombusviruses are not targeted but trigger post-transcriptional gene silencing against their helper virus

Szittya, G., Molnar, A., Silhavy, D., Hornyik, C. & Burgyan, J., Feb 2002, In: Plant Cell. 14, 2, p. 359-372 14 p.

2001

Tissue-specific signal(s) activate the promoter of a metallocarboxypeptidase inhibitor gene family in potato tuber and berry

Molnar, A., Lovas, A., Banfalvi, Z., Lakatos, L., Polgar, Z. & Horvath, S., Jun 2001, In: Plant molecular biology. 46, 3, p. 301-311 11 p.