Publications

Publications from the lab.

2020s

2025

A pilot study of a ketogenic diet in bipolar disorder: clinical, metabolic and magnetic resonance spectroscopy findings

Campbell, I. H., Needham, N., Grossi, H., Kamenska, I., Luz, S., Sheehan, S., Thompson, G., Thrippleton, M. J., Gibbs, M. C., Leitao, J., Moses, T., Burgess, K., Rigby, B. P., Simpson, S. A., McIntosh, E., Brown, R., Meadowcroft, B., Creasy, F., Mitchell-Grigorjeva, M., Norrie, J., & 6 others, 25 Feb 2025, In: BJPsych Open. 11, 2, 8 p., e34.

 

Metabolic biomarkers of clinical outcomes in severe mental illness (METPSY): protocol for a prospective observational study in the Hub for metabolic psychiatry

Rakshasa-Loots, A. M., Steyn, C., Swiffen, D., Marwick, K. F. M., Semple, R. K., Reynolds, R. M., Burgess, K., Lawrie, S. M., Lightman, S. L., Luz, S. & Smith, D. J., 13 Feb 2025, (E-pub ahead of print) In: BMC Psychiatry. 25, 1, p. 122

 

Pilot study of a ketogenic diet in bipolar disorder: a process evaluation

P. rigby, B., Needham, N., Grossi, H., Kamenska, I., H. campbell, I., Meadowcroft, B., Creasy, F., Fisher, C., Bahuguna, P., Norrie, J., Thompson, G., C. gibbs, M., Mitchell-Grigorjeva, M., Mclellan, A., Moses, T., Burgess, K., Brown, R., J. thrippleton, M., Campbell, H., J. smith, D., & 1 others, 21 Jan 2025, (E-pub ahead of print) In: BMC Psychiatry. 25, 1

 

2024

Optimisation of surfactin yield in Bacillus using data-efficient active learning and high-throughput mass spectrometry

Albornoz, R. V., Oyarzún, D. & Burgess, K., Dec 2024, In: Computational and Structural Biotechnology Journal. 23, p. 1226-1233 8 p.

 

Nanotopography Influences Host–Pathogen Quorum Sensing and Facilitates Selection of Bioactive Metabolites in Mesenchymal Stromal Cells and Pseudomonas aeruginosa Co-Cultures: ACS Applied Materials & Interfaces

Cuahtecontzi Delint, R., Ishak, M. I., Tsimbouri, P. M., Jayawarna, V., Burgess, K. V. E., Ramage, G., Nobbs, A. H., Damiati, L., Salmeron-Sanchez, M., Su, B. & Dalby, M. J., 21 Aug 2024, In: ACS Applied Materials & Interfaces. 16, 33, p. 43374-43386 13 p.

 

2023

An integrated transcriptomic and metabolomic approach to investigate the heterogeneous Candida albicans biofilm phenotype

Delaney, C., Short, B., Rajendran, R., Kean, R., Burgess, K., Williams, C., Munro, C. A. & Ramage, G., 1 Dec 2023, In: Biofilm. 5, 12 p., 100112.

 

Pilot study of a ketogenic diet in bipolar disorder

Needham, N., Campbell, I., Grossi, H., Kamenska, I., Rigby, B., Simpson, S. A., McIntosh, E., Bahuguna, P., Meadowcroft, B., Creasy, F., Mitchell-Grigorjeva, M., Norrie, J., Thompson, G., Gibbs, M., McLellan, A., Fisher, C., Moses, T., Burgess, K. E. V., Brown, R., Thrippleton, M. J., & 2 others, 10 Oct 2023, In: BJPsych Open. 9, 6, 8 p., e176.

 

Streamlined identification of strain engineering targets for bioprocess improvement using metabolic pathway enrichment analysis

Cortada Garcia, J., Daly, R., Arnold, S. A. & Burgess, K., 10 Aug 2023, In: Scientific Reports. 13, 14 p., 12990 .

 

Right in two: capabilities of ion mobility spectrometry for untargeted metabolomics

Moses, T. & Burgess, K., 4 Aug 2023, In: Frontiers in Molecular Biosciences. 10, 1230282.

 

Metabolic insights into phosphofructokinase inhibition in bloodstream-form trypanosomes

Nare, Z., Moses, T., Burgess, K. E. V., Schnaufer, A., Walkinshaw, M. D. & Michels, P., 14 Feb 2023, In: Frontiers in Cellular and Infection Microbiology. 13, p. 1-9 9 p., 1129791.

 

2022

On-line untargeted metabolomics monitoring of an escherichia coli succinate fermentation process

Cortada-Garcia, J., Haggarty, J., Moses, T., Daly, R., Arnold, S. A. & Burgess, K., 1 Oct 2022, In: Biotechnology and Bioengineering. 119, 10, p. 2757-2769 13 p.

 

Metabolomic profiling of end-stage heart failure secondary to chronic chagas cardiomyopathy

Díaz, M. L., Burgess, K., Burchmore, R., Gómez, M. A., Gómez-Ochoa, S. A., Echeverría, L. E., Morillo, C. & González, C. I., 9 Sept 2022, In: International Journal of Molecular Sciences. 23, 18, 18 p., 10456.

 

Mass spectral molecular networking to profile the metabolome of biostimulant bacillus strains

Nephali, L., Steenkamp, P., Burgess, K., Huyser, J., Brand, M., van der Hooft, J. J. J. & Tugizimana, F., 9 Jun 2022, In: Frontiers in plant science. 13, 14 p., 920963.

 

Rapid HILIC-Z ion mobility mass spectrometry (RHIMMS) method for untargeted metabolomics of complex biological samples

Picmanova, M., Moses, T., Cortada Garcia, J., Barrett, G., Florance, H., Pandor, S. & Burgess, K. E. V., 28 Feb 2022, In: Metabolomics : Official journal of the Metabolomic Society. 18, 3, p. 16 12 p., 16.

 

Materials-driven fibronectin assembly on nanoscale topography enhances mesenchymal stem cell adhesion, protecting cells from bacterial virulence factors and preventing biofilm formation

Damiati, L. A., Tsimbouri, M. P., Hernandez, V. L., Jayawarna, V., Ginty, M., Childs, P., Xiao, Y., Burgess, K., Wells, J., Sprott, M. R., Meek, R. M. D., Li, P., Oreffo, R. O. C., Nobbs, A., Ramage, G., Su, B., Salmeron-Sanchez, M. & Dalby, M. J., 1 Jan 2022, In: Biomaterials. 280, 121263.

 

2021

Metabolomics for the diagnosis of influenza

Burgess, K. & Rankin, N., 5 Oct 2021, In: EBioMedicine. 72, 103599.

 

A metabolomic landscape of maize plants treated with a microbial biostimulant under well-watered and drought conditions

Nephali, L., Moodley, V., Piater, L., Steenkamp, P., Buthelezi, N., Dubery, I., Burgess, K., Huyser, J. & Tugizimana, F., 3 Jun 2021, In: Frontiers in plant science. 12, 676632, 15 p.

 

Inhibition of glycolysis and mitochondrial respiration promotes radiosensitisation of neuroblastoma and glioma cells

Nile, D. L., Rae, C., Walker, D. J., Waddington, J. C., Vincent, I., Burgess, K., Gaze, M. N., Mairs, R. J. & Chalmers, A. J., 19 May 2021, In: Cancer and Metabolism. 9, 1, 15 p., 24.

 

A metabolomics-based approach to identify lineage guiding molecules in Pericyte cultures

Alakpa, E. V., West, C. C., Goldie, L., Harper, M. M., Burgess, K., Ulijn, R. V. & Dalby, M. J., 13 Feb 2021, Pericytes : Methods and Protocols. Humana Press, Vol. 2235. p. 47-59 13 p. (Methods in Molecular Biology; vol. 2235).

 

Ranking metabolite sets by their activity levels

Mcluskey, K., Wandy, J., Vincent, I., Van Der Hooft, J. J. J., Rogers, S., Burgess, K. & Daly, R., 11 Feb 2021, In: Metabolites. 11, 2

 

2020

Schistosoma haematobium infection is associated with alterations in energy and purine-related metabolism in preschool-aged children

Osakunor, D., Mduluza, T., Osei-Hyiaman, D., Burgess, K. E. V., Woolhouse, M. & Mutapi, F., 14 Dec 2020, In: PLoS Neglected Tropical Diseases. 14, 12, 23 p., e0008866.

 

Biostimulants for plant growth and mitigation of abiotic stresses: A metabolomics perspective

Nephali, L., Piater, L. A., Dubery, I. A., Patterson, V., Huyser, J., Burgess, K. & Tugizimana, F., 10 Dec 2020, In: Metabolites. 10, 12, 26 p., 505.

 

Postmortomics: The potential of untargeted metabolomics to highlight markers for time since death

Pesko, B. K., Weidt, S., McLaughlin, M., Wescott, D. J., Torrance, H., Burgess, K. & Burchmore, R., 4 Nov 2020, In: OMICS A Journal of Integrative Biology. 24, 11, p. 649-659 11 p.

 

Running on empty: A metabolomics approach to investigating changing energy metabolism during fasted exercise and rest

Blackburn, G., Hay, J., Skagen, C., Paul, E., Achcar, F., Wilson, J., Best, C., Manson, E., Burgess, K., Barrett, M. P. & Gill, J. M. R., 8 Oct 2020, In: Metabolites. 10, 10, p. 1-11 11 p., 399.

 

Changes in plasma itaconate elevation in early rheumatoid arthritis patients elucidates disease activity associated macrophage activation

Daly, R., Blackburn, G., Best, C., Goodyear, C. S., Mudaliar, M., Burgess, K., Stirling, A., Porter, D., McInnes, I. B., Barrett, M. P. & Dale, J., 10 Jun 2020, In: Metabolites. 10, 6, p. 1-12 12 p., 241.

 

Functional colour genes and signals of selection in colour polymorphic salamanders

Burgon, J. D., Vieites, D. R., Jacobs, A., Weidt, S. K., Gunter, H. M., Steinfartz, S., Burgess, K., Mable, B. K. & Elmer, K. R., 11 Mar 2020, In: Molecular Ecology. p. 1284-1299

Research output: Contribution to journal › Article › peer-review

2019

Changing environments and genetic variation: Natural variation in inbreeding does not compromise short-term physiological responses

Buckley, J., Daly, R., Cobbold, C. A., Burgess, K. & Mable, B. K., 20 Nov 2019, In: Proceedings of the Royal Society B: Biological Sciences. 286, 1915, 20192109.

 

Multi-layer controls of Cas9 activity coupled with ATP synthase over-expression for efficient genome editing in streptomyces

Wang, K., Zhao, Q., Liu, Y., Sun, C., Chen, X., Burchmore, R., Burgess, K., Li, Y. & Mao, X., 1 Nov 2019, In: Frontiers in Bioengineering and Biotechnology. 7

 

Pharmacometabolomics of meglumine antimoniate in patients with cutaneous leishmaniasis

Vargas, D. A., Prieto, M. D., Martínez-Valencia, A. J., Cossio, A., Burgess, K. E. V., Burchmore, R. J. S. & Adelaida Gómez, M., 20 Jun 2019, In: Frontiers in pharmacology. 10, 657.

 

High-throughput quantification of carboxymethyl lysine in serum and plasma using high-resolution accurate mass Orbitrap mass spectrometry

Rankin, N. J., Burgess, K., Weidt, S., Wannamethee, G., Sattar, N. & Welsh, P., 4 Mar 2019, In: Annals of Clinical Biochemistry. 56, 3, p. 397-407 11 p.

 

Substantial extracellular metabolic differences found between phylogenetically closely related probiotic and pathogenic strains of Escherichia coli

Van Der Hooft, J. J. J., Goldstone, R. J., Harris, S., Burgess, K. & Smith, D. G. E., 19 Feb 2019, In: Frontiers in Microbiology. 10, FEB, 252.

 

2018

Unexpected differential metabolic responses of Campylobacter jejuni to the abundant presence of glutamate and fucose

van der Hooft, J. J. J., Alghefari, W., Watson, E., Everest, P., Morton, F. R., Burgess, K. E. V. & Smith, D. G. E., 23 Oct 2018, In: Metabolomics. 14, 11, 144.

 

MetaboCraft: building a Minecraft plugin for metabolomics

Megalios, A., Daly, R. & Burgess, K., 1 Aug 2018, In: Bioinformatics. 34, 15, p. 2693-2694 2 p.

 

Minimally-destructive atmospheric ionisation mass spectrometry authenticates authorship of historical manuscripts

Newton, J., Ramage, G., Gadegaard, N., Zachs, W., Rogers, S., Barrett, M. P., Carruthers, G. & Burgess, K., 26 Jul 2018, In: Scientific Reports. 8, 1, p. 10944 7 p.

 

2017

MetaNetter 2: A Cytoscape plugin for ab initio network analysis and metabolite feature classification

Burgess, K. E. V., Borutzki, Y., Rankin, N., Daly, R. & Jourdan, F., 15 Dec 2017, In: Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 1071, p. 68-74 7 p.

 

Stimulation of 3D osteogenesis by mesenchymal stem cells using a nanovibrational bioreactor

Tsimbouri, P. M., Childs, P. G., Pemberton, G. D., Yang, J., Jayawarna, V., Orapiriyakul, W., Burgess, K., González-García, C., Blackburn, G., Thomas, D., Vallejo-Giraldo, C., Biggs, M. J. P., Curtis, A. S. G., Salmerón-Sánchez, M., Reid, S. & Dalby, M. J., 12 Sept 2017, In: Nature Biomedical Engineering. 1, 9, p. 758-770

 

PiMP my metabolome: An integrated, web-based tool for LC-MS metabolomics data

Gloaguen, Y., Morton, F., Daly, R., Gurden, R., Rogers, S., Wandy, J., Wilson, D., Barrett, M. & Burgess, K., 14 Aug 2017, In: Bioinformatics. 33, 24, p. 4007-4009 3 p.

 

Novel compounds targeting the enterohemorrhagic Escherichia coli type three secretion system reveal insights into mechanisms of secretion inhibition

Zambelloni, R., Connolly, J. P. R., Uribe, A. H., Burgess, K., Marquez, R. & Roe, A. J., 1 Aug 2017, In: Molecular Microbiology. 105, 4, p. 606-619 14 p.

 

Nacre Topography Produces Higher Crystallinity in Bone than Chemically Induced Osteogenesis

Alakpa, E. V., Burgess, K. E. V., Chung, P., Riehle, M. O., Gadegaard, N., Dalby, M. J. & Cusack, M., 25 Jul 2017, In: ACS Nano. 11, 7, p. 6717-6727 11 p.

 

Unsupervised discovery and comparison of structural families across multiple samples in untargeted metabolomics

van der Hooft, J. JJ., Wandy, J., Young, F., Padmanabhan, S., Gerasimidis, K., Burgess, K. EV., Barrett, M. P. & Rogers, S., 18 Jul 2017, In: Analytical Chemistry. 89, 14, p. 7569-7577 9 p.

 

Sterol 14α-demethylase mutation leads to amphotericin B resistance in Leishmania mexicana

Mwenechanya, R., Kovářová, J., Dickens, N. J., Manikhandan, M., Herzyk, P., Vincent, I. M., Weidt, S. K., Burgess, K. E., Burchmore, R. J. S., Pountain, A. W., Smith, T. K., Creek, D. J., Kim, D. H., Lepesheva, G. I. & Barrett, M. P., 16 Jun 2017, In: PLoS Neglected Tropical Diseases. 11, 6, 21 p., e0005649.

 

Candida albicans mycofilms support Staphylococcus aureus colonization and enhances miconazole resistance in dual-species interactions

Kean, R., Rajendran, R., Haggarty, J., Townsend, E. M., Short, B., Burgess, K. E., Lang, S., Millington, O., Mackay, W. G., Williams, C. & Ramage, G., 23 Feb 2017, In: Frontiers in Microbiology. 8, FEB, 258.

 

Integration of proteomics and metabolomics to elucidate metabolic adaptation in Leishmania

Akpunarlieva, S., Weidt, S., Lamasudin, D., Naula, C., Henderson, D., Barrett, M., Burgess, K. & Burchmore, R., 23 Feb 2017, In: Journal of proteomics. 155, p. 85-98 14 p.

 

Recent advances in liquid and gas chromatography methodology for extending coverage of the metabolome

Haggarty, J. & Burgess, K. EV., 1 Feb 2017, In: Current opinion in biotechnology. 43, p. 77-85 9 p.

 

Nanotopography controls cell cycle changes involved with skeletal stem cell self-renewal and multipotency

Lee, L. C. Y., Gadegaard, N., de Andrés, M. C., Turner, L. A., Burgess, K. V., Yarwood, S. J., Wells, J., Salmeron-Sanchez, M., Meek, D., Oreffo, R. O. C. & Dalby, M. J., Feb 2017, In: Biomaterials. 116, p. 10-20 11 p.

 

2016

Topic modeling for untargeted substructure exploration in metabolomics

van der Hooft, J. J. J., Wandy, J., Barrett, M. P., Burgess, K. E. V. & Rogers, S., 29 Nov 2016, In: Proceedings of the National Academy of Sciences (PNAS). 113, 48, p. 13738-13743 6 p.

 

A novel targeted/untargeted GC-Orbitrap metabolomics methodology applied to Candida albicans and Staphylococcus aureus biofilms

Weidt, S., Haggarty, J., Kean, R., Cojocariu, C. I., Silcock, P. J., Rajendran, R., Ramage, G. & Burgess, K. E. V., 5 Nov 2016, In: Metabolomics. 12, 12, 189.

 

Tunable supramolecular hydrogels for selection of lineage-guiding metabolites in stem cell cultures

Alakpa, E. V., Jayawarna, V., Lampel, A., Burgess, K., West, C. C., Bakker, S. C. J., Roy, S., Javid, N., Fleming, S., Lamprou, D. A., Yang, J., Miller, A., Urquhart, A. J., Frederix, P. W. J. M., Hunt, N. T., Péault, B., Ulijn, R. V. & Dalby, M. J., 27 Jul 2016, In: Chem. 1, 2, p. 298-319 22 p.

 

Dynamic surfaces for the study of mesenchymal stem cell growth through adhesion regulation

Roberts, J. N., Sahoo, J. K., McNamara, L. E., Burgess, K. V., Yang, J., Alakpa, E. V., Anderson, H. J., Hay, J., Turner, L. A., Yarwood, S. J., Zelzer, M., Oreffo, R. O. C., Ulijn, R. V. & Dalby, M. J., 26 Jul 2016, In: ACS Nano. 10, 7, p. 6667-6679 13 p.

 

Mastitomics, the integrated omics of bovine milk in an experimental model of Streptococcus uberis mastitis: 3. Untargeted metabolomics

Thomas, F. C., Mudaliar, M., Tassi, R., McNeilly, T. N., Burchmore, R., Burgess, K., Herzyk, P., Zadoks, R. N. & Eckersall, P. D., 14 Jul 2016, In: Molecular BioSystems. 12, 9, p. 2762-2769 8 p.

 

Urinary antihypertensive drug metabolite screening using molecular networking coupled to high-resolution mass spectrometry fragmentation

Van Der Hooft, J. JJ., Padmanabhan, S., Burgess, K. EV. & Barrett, M. P., 5 Jul 2016, In: Metabolomics. 12, 7, p. 125 15 p.

 

Glycolysis and pyrimidine biosynthesis are required for replication of adherent–invasive escherichia coli in macrophages

Thompson, A. P., O’Neill, I., Smith, E. J., Catchpole, J., Fagan, A., Burgess, K. E. V., Carmody, R. J. & Clarke, D. J., 1 Jun 2016, In: Microbiology (United Kingdom). 162, 6, p. 954-965 12 p., 000289.

 

A novel metabolomic approach used for the comparison of Staphylococcus aureus planktonic cells and biofilm samples

Stipetic, L. H., Dalby, M. J., Davies, R. L., Morton, F. R., Ramage, G. & Burgess, K. E. V., 8 Mar 2016, (E-pub ahead of print) In: Metabolomics. 12, 4, 75.

 

2015

LC–MS-based absolute metabolite quantification: Application to metabolic flux measurement in trypanosomes

Kim, D. H., Achcar, F., Breitling, R., Burgess, K. E. & Barrett, M. P., 9 Dec 2015, In: Metabolomics. 11, 6, p. 1721-1732 12 p.

 

Asymmetric cell division and its role in cell fate determination in the green alga Tetraselmis indica

Arora, M., Anil, A. C., Burgess, K., Delany, J. & Mesbahi, E., 4 Dec 2015, In: Journal of Biosciences. 40, 5, p. 921-927 7 p.

 

Draft genome sequence of isolate Staphylococcus aureus LHSKBClinical, isolated from an infected hip

Stipetic, L. H., Hamilton, G., Dalby, M. J., Davies, R. L., Meek, R. M. D., Ramage, G., Smith, D. G. E. & Burgess, K. E. V., 30 Apr 2015, In: Genome announcements. 3, 2, e00336-15.

 

The host metabolite D-serine contributes to bacterial niche specificity through gene selection

Connolly, J. P. R., Goldstone, R. J., Burgess, K., Cogdell, R. J., Beatson, S. A., Vollmer, W., Smith, D. G. E. & Roe, A. J., 17 Mar 2015, In: The ISME Journal: Multidisciplinary Journal of Microbial Ecology. 9, 4, p. 1039-51 13 p.

 

Probing the metabolic network in bloodstream-form trypanosoma brucei using untargeted metabolomics with stable isotope labelled glucose

Creek, D. J., Mazet, M., Achcar, F., Anderson, J., Kim, D. H., Kamour, R., Morand, P., Millerioux, Y., Biran, M., Kerkhoven, E. J., Chokkathukalam, A., Weidt, S. K., Burgess, K. E. V., Breitling, R., Watson, D. G., Bringaud, F. & Barrett, M. P., 16 Mar 2015, In: PLoS Pathogens. 11, 3, p. 1-25 25 p., e1004689.

 

Potent trypanocidal curcumin analogs bearing a monoenone linker motif act on Trypanosoma brucei by forming an adduct with trypanothione

Alkhaldi, A. A. M., Creek, D. J., Ibrahim, H., Kim, D. H., Quashie, N. B., Burgess, K. E., Changtam, C., Barrett, M. P., Suksamrarn, A. & De Koning, H. P., 1 Mar 2015, In: Molecular Pharmacology. 87, 3, p. 451-464 14 p.

 

Systems biology approaches applied to regenerative medicine

McNamara, L. E., Turner, L-A. & Burgess, K. V., 10 Feb 2015, In: Current Pathobiology Reports. 3, 1, p. 37-45 9 p.

 

Serially coupling hydrophobic interaction and reversed-phase chromatography with simultaneous gradients provides greater coverage of the metabolome

Haggarty, J., Oppermann, M., Dalby, M. J., Burchmore, R. J., Cook, K., Weidt, S. & Burgess, K. EV., 11 Jan 2015, In: Metabolomics. 11, 5, p. 1465-1470 6 p.

 

Enhanced acylcarnitine annotation in high-resolution mass spectrometry data: Fragmentation analysis for the classification and annotation of acylcarnitines

van der Hooft, J. J. J., Ridder, L., Barrett, M. P. & Burgess, K. E. V., 1 Jan 2015, In: Frontiers in Bioengineering and Biotechnology. 3, 26.

 

2014

The emergence of proton nuclear magnetic resonance metabolomics in the cardiovascular arena as viewed from a clinical perspective

Rankin, N. J., Preiss, D., Welsh, P., Burgess, K. E. V., Nelson, S. M., Lawlor, D. A. & Sattar, N., 1 Nov 2014, In: Atherosclerosis. 237, 1, p. 287-300 14 p.

 

Nanotopographical induction of osteogenesis through adhesion, bone morphogenic protein cosignaling, and regulation of microRNAs

Yang, J., McNamara, L. E., Gadegaard, N., Alakpa, E. V., Burgess, K. V., Meek, R. M. D. & Dalby, M. J., 28 Oct 2014, In: ACS Nano. 8, 10, p. 9941-9953 13 p.

 

Recovery from rapamycin: Drug-insensitive activity of yeast TORC1 supports residual proliferation that dilutes rapamycin among progeny cells

Evans, S. K., Burgess, K. EV. & Gray, J. V., 7 Aug 2014, In: Journal of Biological Chemistry. 289, 38, p. 26554-26565 12 p.

 

MetAssign: Probabilistic annotation of metabolites from LC--MS data using a Bayesian clustering approach

Daly, R., Rogers, S., Wandy, J., Jankevics, A., Burgess, K. EV. & Breitling, R., 9 Jun 2014, In: Bioinformatics. 30, 19, p. 2764-2771 8 p.

 

The metabolic enzyme AdhE controls the virulence of Escherichia coli O157:H7

Beckham, K. S. H., Connolly, J. P. R., Ritchie, J. M., Wang, D., Gawthorne, J. A., Tahoun, A., Gally, D. L., Burgess, K., Burchmore, R. J., Smith, B. O., Beatson, S. A., Byron, O., Wolfe, A. J., Douce, G. R. & Roe, A. J., 21 May 2014, In: Molecular Microbiology. 93, 1, p. 199-211 13 p.

 

Topographically targeted osteogenesis of mesenchymal stem cells stimulated by inclusion bodies attached to polycaprolactone surfaces

Seras-Franzoso, J., Tsimbouri, P. M., Burgess, K. V., Unzueta, U., Garcia-Fruitos, E., Vazquez, E., Villaverde, A. & Dalby, M. J., 20 Feb 2014, In: Nanomedicine. 9, 2, p. 207-220 14 p.

 

Untargeted metabolomic analysis of miltefosine action in Leishmania infantum reveals changes to the internal lipid metabolism

Vincent, I. M., Weidt, S., Rivas, L., Burgess, K., Smith, T. K. & Ouellette, M., Feb 2014, In: International Journal for Parasitology: Drugs and Drug Resistance. 4, 1, p. 20-27 8 p.

 

Diagnosing dietary intake in C 57 Bl6 mice by using serum metabolomics: T6: S28. 49

Speakman, J., Valencak, T., Burgess, K. & Gruen, B., 2014, In: Obesity Reviews. 15, S2

 

Experimental and translational neuroscience A urinary metabolomic analysis of patients with minor stroke and transient ischemic attack: WSC-1255

Keenan, C., Burgess, K., Barrett, M., Husi, H., Delles, C., Walters, M. & Dawson, J., 2014, In: International Journal of Stroke. 9

 

2013

Nanotopographical effects on mesenchymal stem cell morphology and phenotype

Tsimbouri, P., Gadegaard, N., Burgess, K., White, K., Reynolds, P., Herzyk, P., Oreffo, R. & Dalby, M. J., 30 Sept 2013, In: Journal of cellular biochemistry. 115, 2, p. 380-390 11 p.

 

Mitochondrial substrate availability and its role in lipid-induced insulin resistance and proinflammatory signaling in skeletal muscle

Lipina, C., Macrae, K., Suhm, T., Weigert, C., Blachnio-Zabielska, A., Baranowski, M., Gorski, J., Burgess, K. & Hundal, H. S., 24 Sept 2013, In: Diabetes . 62, 10, p. 3426-3436 11 p.

 

Oxidative stress rather than triglyceride accumulation perturbs glutathione metabolism in an in vitro model of cellular steatosis

Lockman, K. A., Nelson, L. J., Manning, J. R., Burgess, K. E., Martin, S. F., Le Bihan, T., Dunbar, D. R., Morley, S. D., Hayes, P. C. & Plevris, J. N., Jun 2013, In: Gut. 62, Suppl 1 :A1–A306, p. A3-A3 1 p., OC-007.

 

Anti-GM2 ganglioside antibodies are a biomarker for acute canine polyradiculoneuritis

Rupp, A., Galban-Horcajo, F., Bianchi, E., Dondi, M., Penderis, J., Cappell, J., Burgess, K., Matiasek, K., McGonigal, R. & Willison, H. J., 22 Mar 2013, In: Journal of the peripheral nervous system. 18, 1, p. 75-88 14 p.

 

Pyrimidine salvage in trypanosoma brucei bloodstream forms and the trypanocidal action of halogenated pyrimidines

Ali, J. A. M., Creek, D. J., Burgess, K., Allison, H. C., Field, M. C., Mäser, P. & De Koning, H. P., 1 Feb 2013, In: Molecular Pharmacology. 83, 2, p. 439-453 15 p.

 

HEPSYS-II METABOLOMICS PROFILING OF AN IN VITRO MODEL OF CELLULAR STEATOSIS: DICARBOXYLIC ACIDS AND EICOSANOIDS AS MARKERS OF ENHANCED LIPID PEROXIDATION AND FATTY ACID OXIDATION DYSREGULATION

Lockman, K. A., Treskes, P., Nelson, L., Burgess, K., Lee, P., Morley, S. D., Hayes, P. & Plevris, J., Feb 2013.

 

2012

Stable isotope-assisted metabolomics for network-wide metabolic pathway elucidation

Creek, D. J., Chokkathukalam, A., Jankevics, A., Burgess, K. EV., Breitling, R. & Barrett, M. P., 16 Oct 2012, In: Analytical Chemistry. 84, 20, p. 8442-8447 6 p.

 

Development of biomaterials for cellular differentiation using a metabolomics approach

Alakpa, EV., Burgess, K., Jayawarna, V., Ulijn, R. & Dalby, M., 30 Sept 2012, In: Journal of Tissue Engineering and Regenerative Medicine. 6, s1, p. 238-238 1 p.

 

Metabolomics: a valuable tool for stem cell monitoring in regenerative medicine

McNamara, L. E., Sjöström, T., Meek, RM. D., Oreffo, R. OC., Su, B., Dalby, M. J. & Burgess, K. EV., 7 Aug 2012, In: Journal of the Royal Society. Interface. 9, 73, p. 1713-1724 12 p.

 

PMO-130 Altered acetyl-coa metabolism in hepatic mitochondrial impairment in in vitro models of hepatic cellular steatosis

Lockman, K., Burgess, K. E., Lee, P., Pryde, A., Hayes, P. C., Filippi, C. & Plevris, J. N., 31 Jul 2012, In: Gut. 61, Suppl 2, p. A125-A126 2 p.

 

PTU-044 Hepatic/endothelial cell co-culture; establishing optimal conditions for liver tissue engineering

Navarro, M., Nelson, L., Burgess, K., Tura, O., Samuel, K. & Plevris, J., 31 Jul 2012, p. A202-A202.

 

Untargeted metabolomics reveals a lack of synergy between nifurtimox and eflornithine against Trypanosoma brucei

Vincent, I. M., Creek, D. J., Burgess, K., Woods, D. J., Burchmore, R. JS. & Barrett, M. P., 1 May 2012, In: PLoS Neglected Tropical Diseases. 6, 5, e1618.

 

IDEOM: an Excel interface for analysis of LC--MS-based metabolomics data

Creek, D. J., Jankevics, A., Burgess, K. EV., Breitling, R. & Barrett, M. P., 1 Apr 2012, In: Bioinformatics. 28, 7, p. 1048-1049 2 p.

 

Strategies to dissect parasite proteomes

Burgess, K. & R, B., 20 Feb 2012, In: Parasitology. p. 1119-1130

 

Characterisation of peptide biomaterials innate metabolites that direct stem cell differentiation in vitro

Alakpa, E., Jayarwarna, V., Burgess, K. & Dalby, M., 2012, In: European Cell and Materials. 23, Sup 4, p. 50-50 1 p.

 

Oxidative stress rather than triglyceride accumulation is a determinant of mitochondrial dysfunction in in vitro models of hepatic cellular steatosis

Lockman, K. A., Baren, J. P., Pemberton, C. J., Baghdadi, H., Burgess, K. E., Plevris-Papaioannou, N., Lee, P., Howie, F., Beckett, G., Pryde, A., Jaap, A. J., Hayes, P. C., Filippi, C. & Plevris, J., 2012, In: Liver International. 32, 7, p. 1079-92 14 p.

 

2011

Pathos: a web facility that uses metabolic maps to display experimental changes in metabolites identified by mass spectrometry

Leader, D. P., Burgess, K., Creek, D. & Barrett, M. P., 30 Nov 2011, In: Rapid communications in mass spectrometry. 25, 22, p. 3422-3426 5 p.

 

Semi-targeted analysis of metabolites using capillary-flow ion chromatography coupled to high-resolution mass spectrometry

Burgess, K., Creek, D., Dewsbury, P., Cook, K. & Barrett, M. P., 30 Nov 2011, In: Rapid communications in mass spectrometry. 25, 22, p. 3447-3452 6 p.

 

Toward Global Metabolomics Analysis with Hydrophilic Interaction Liquid Chromatography–Mass Spectrometry: Improved Metabolite Identification by Retention Time Prediction

Creek, D. J., Jankevics, A., Breitling, R., Watson, D. G., Barrett, M. P. & Burgess, K. EV., 15 Nov 2011, In: Analytical Chemistry. 83, 22, p. 8703-8710 8 p.

 

Skeletal stem cell physiology on functionally distinct titania nanotopographies

McNamara, L. E., Sjöström, T., Burgess, K. E. V., Kim, J. J. W., Liu, E., Gordonov, S., Moghe, P. V., Meek, R. M. D., Oreffo, R. O. C., Su, B. & Dalby, M. J., 1 Oct 2011, In: Biomaterials. 32, 30, p. 7403-7410 8 p.

 

Nanoscale surfaces for the long-term maintenance of mesenchymal stem cell phenotype and multipotency

McMurray, R. J., Gadegaard, N., Tsimbouri, P. M., Burgess, K. V., McNamara, L. E., Tare, R., Murawski, K., Kingham, E., Oreffo, R. O. C. & Dalby, M. J., 17 Jul 2011, In: Nature Materials. 10, 8, p. 637-644 8 p.

 

Tissue engineering vascularized human liver organoids: study of morphology, metabolomics and phenotypic expression of transitional 2D/3D co-cultures of hepatic C3A cells with endothelial progenitors

Nelson, LJ., Burgess, K., Tura, O., Navarro, M., Samuel, K., Hayes, PC., Turner, M. & Plevris, JN., Mar 2011, In: Journal of Hepatology. 54, SUPPL. 1., p. S431-S431 1 p., 1091.

 

Characterisation of mesenchymal stem cell responses to titanium nanopillars for orthopaedic applications

McNamara, LE., Sjöström, T., Burgess, K., Oreffo, ROC., Su, B. & Dalby, MJ., 2011, In: eCells and Materials Journal (eCM). 22, Suppl. 2, p. 7 1 p.

 

Elucidating cellular reaction to biomaterial substrates using a metabolomics approach

Alakpa, E., Jayawarna, V., Burgess, K. & Dalby, M., 2011, In: eCells and Materials Journal (eCM). 22, SUPPL. 3, p. 18 1 p.

 

Mechanotransduction and skeletal stem cell differentiation in response to bioactive nanotopography

Tsimbouri, P., Gadegaard, N., Burgess, K., Kingham, E., Oreffo, ROC. & Dalby, MJ., 2011, In: Histology and Histopathology: Cellular and Molecular Biology. 26, S1, 2 p., 31.012.

 

Metabolomic investigation of MSC responses to titania nanopillars

McNamara, L. E., Sjöström, T., Burgess, K. V., Kim, J., Liu, E., Gordonov, S., Moghe, P., Oreffo, R. OC., Su, B. & Dalby, M. J., 2011, In: eCells and Materials Journal (eCM). 22, SUPPL. 3, p. 74 1 p.

 

2010

A fluorescence-based assay for the uptake of CPD0801 (DB829) by African trypanosomes

Ward, C. P., Burgess, K. EV., Burchmore, R. JS., Barrett, M. P. & de Koning, H. P., 31 Dec 2010, In: Molecular and Biochemical Parasitology. 174, 2, p. 145-149 5 p.

 

Effects of a surface topography composite with puerariae radix on human STRO-1-positive stem cells

Kantawong, F., Burgess, K. EV., Jayawardena, K., Hart, A., Riehle, M. O., Oreffo, R. O., Dalby, M. J. & Burchmore, R., 30 Sept 2010, In: Acta Biomaterialia. 6, 9, p. 3694-3703 10 p.


2009

Whole proteome analysis of osteoprogenitor differentiation induced by disordered nanotopography and mediated by ERK signalling

Kantawong, F., Burgess, K. EV., Jayawardena, K., Hart, A., Burchmore, R. J., Gadegaard, N., Oreffo, R. OC. & Dalby, M. J., 30 Sept 2009, In: Biomaterials. 30, 27, p. 4723-4731 9 p.

 

Performance of five different electrospray ionisation sources in conjunction with rapid monolithic column liquid chromatography and fast MS/MS scanning

Burgess, K. E. V., Lainson, A., Imrie, L., Fraser-Pitt, D., Yaga, R., Smith, D. GE., Swart, R., Pitt, A. R. & Inglis, N. F., 17 Mar 2009, In: Proteomics. 9, 6, p. 1720-1726 7 p.

 

2008

Sensitive, Specific and Quantitative FT-ICR Mass Spectrometry of Combinatorial Post-Translational Modifications in Intact Histone H4

Mackay, L., Ramsahoye, B., Burgess, K., Cook, K., Weidt, S., Creanor, J., Harrison, D., Langridge-Smith, P., Hupp, T. & Hayward, L., Jun 2008, In: Analytical Chemistry. 80, 11, p. 4147-4153